Cargando…

Methylation analysis of Klebsiella pneumoniae from Portuguese hospitals

Klebsiella pneumoniae is an important nosocomial infectious agent with a high antimicrobial resistance (AMR) burden. The application of long read sequencing technologies is providing insights into bacterial chromosomal and putative extra-chromosomal genetic elements (PEGEs) associated with AMR, but...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spadar, Anton, Perdigão, João, Phelan, Jody, Charleston, James, Modesto, Ana, Elias, Rita, de Sessions, Paola Florez, Hibberd, Martin L., Campino, Susana, Duarte, Aida, Clark, Taane G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985491/ https://www.ncbi.nlm.nih.gov/pubmed/33753763 http://dx.doi.org/10.1038/s41598-021-85724-2

Ejemplares similares

Genomic Epidemiology of Carbapenemase Producing Klebsiella pneumoniae Strains at a Northern Portuguese Hospital Enables the Detection of a Misidentified Klebsiella variicola KPC-3 Producing Strain
por: Perdigão, João, et al.
Publicado: (2020)

Whole-genome sequencing resolves a polyclonal outbreak by extended-spectrum beta-lactam and carbapenem-resistant Klebsiella pneumoniae in a Portuguese tertiary-care hospital
por: Perdigão, João, et al.
Publicado: (2020)

Genomic epidemiological analysis of Klebsiella pneumoniae from Portuguese hospitals reveals insights into circulating antimicrobial resistance
por: Spadar, Anton, et al.
Publicado: (2022)

Genomic analysis of hypervirulent Klebsiella pneumoniae reveals potential genetic markers for differentiation from classical strains
por: Spadar, Anton, et al.
Publicado: (2022)

Large-scale genomic analysis of global Klebsiella pneumoniae plasmids reveals multiple simultaneous clusters of carbapenem-resistant hypervirulent strains
por: Spadar, Anton, et al.
Publicado: (2023)

Large-scale reference-free analysis of flavivirus sequences in Aedes aegypti whole genome DNA sequencing data
por: Spadar, Anton, et al.
Publicado: (2023)

Klebsiella pneumoniae and Colistin Susceptibility Testing: Performance Evaluation for Broth Microdilution, Agar Dilution and Minimum Inhibitory Concentration Test Strips and Impact of the “Skipped Well” Phenomenon
por: Elias, Rita, et al.
Publicado: (2021)

A Molecular Perspective on Colistin and Klebsiella pneumoniae: Mode of Action, Resistance Genetics, and Phenotypic Susceptibility
por: Elias, Rita, et al.
Publicado: (2021)

Genome dynamics of high-risk resistant and hypervirulent Klebsiella pneumoniae clones in Dhaka, Bangladesh
por: Hussain, Arif, et al.
Publicado: (2023)

Flavivirus integrations in Aedes aegypti are limited and highly conserved across samples from different geographic regions unlike integrations in Aedes albopictus
por: Spadar, Anton, et al.
Publicado: (2021)

COVID-profiler: a webserver for the analysis of SARS-CoV-2 sequencing data
por: Phelan, Jody, et al.
Publicado: (2022)

Case report: A successfully treated case of community-acquired urinary tract infection due to Klebsiella aerogenes in Bangladesh
por: Mazumder, Razib, et al.
Publicado: (2023)

An integrated in silico immuno-genetic analytical platform provides insights into COVID-19 serological and vaccine targets
por: Ward, Daniel, et al.
Publicado: (2021)

Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally
por: Phelan, Jody, et al.
Publicado: (2018)

Mixed infections in genotypic drug-resistant Mycobacterium tuberculosis
por: Wang, Linfeng, et al.
Publicado: (2023)

An integrated whole genome analysis of Mycobacterium tuberculosis reveals insights into relationship between its genome, transcriptome and methylome
por: Gomez-Gonzalez, Paula J., et al.
Publicado: (2019)

Large-scale genomic analysis of Mycobacterium tuberculosis reveals extent of target and compensatory mutations linked to multi-drug resistant tuberculosis
por: Napier, Gary, et al.
Publicado: (2023)

Identification of two insecticide resistance markers in Ethiopian Anopheles stephensi mosquitoes using a multiplex amplicon sequencing assay
por: Acford-Palmer, Holly, et al.
Publicado: (2023)

A next generation targeted amplicon sequencing method to screen for insecticide resistance mutations in Aedes aegypti populations reveals a rdl mutation in mosquitoes from Cabo Verde
por: Collins, Emma L., et al.
Publicado: (2022)

Zika might not be acting alone: Using an ecological study approach to investigate potential co-acting risk factors for an unusual pattern of microcephaly in Brazil
por: Campos, Monica C., et al.
Publicado: (2018)

Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid
por: Gómez-González, Paula J., et al.
Publicado: (2021)

Robust detection of point mutations involved in multidrug-resistant Mycobacterium tuberculosis in the presence of co-occurrent resistance markers
por: Libiseller-Egger, Julian, et al.
Publicado: (2020)

Portable sequencing of Mycobacterium tuberculosis for clinical and epidemiological applications
por: Gómez-González, Paula J, et al.
Publicado: (2022)

Robust barcoding and identification of Mycobacterium tuberculosis lineages for epidemiological and clinical studies
por: Napier, Gary, et al.
Publicado: (2020)

A modified decision tree approach to improve the prediction and mutation discovery for drug resistance in Mycobacterium tuberculosis
por: Deelder, Wouter, et al.
Publicado: (2022)

Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis
por: Andreu, Nuria, et al.
Publicado: (2017)

Geographical classification of malaria parasites through applying machine learning to whole genome sequence data
por: Deelder, Wouter, et al.
Publicado: (2022)

Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance
por: Oppong, Yaa E. A., et al.
Publicado: (2019)

Emergence of multidrug-resistant Mycobacterium tuberculosis of the Beijing lineage in Portugal and Guinea-Bissau: a snapshot of moving clones by whole-genome sequencing
por: Perdigão, João, et al.
Publicado: (2020)

Whole genome sequencing reveals large deletions and other loss of function mutations in Mycobacterium tuberculosis drug resistance genes
por: Gomes, Laura C., et al.
Publicado: (2021)

TB-ML—a framework for comparing machine learning approaches to predict drug resistance of Mycobacterium tuberculosis
por: Libiseller-Egger, Julian, et al.
Publicado: (2023)

Using genomics to understand the origin and dispersion of multidrug and extensively drug resistant tuberculosis in Portugal
por: Perdigão, João, et al.
Publicado: (2020)

Functional genetic variation in pe/ppe genes contributes to diversity in Mycobacterium tuberculosis lineages and potential interactions with the human host
por: Gómez-González, Paula Josefina, et al.
Publicado: (2023)

Using deep learning to identify recent positive selection in malaria parasite sequence data
por: Deelder, Wouter, et al.
Publicado: (2021)

PrimedRPA: primer design for recombinase polymerase amplification assays
por: Higgins, Matthew, et al.
Publicado: (2019)

Whole genome sequencing of drug resistant Mycobacterium tuberculosis isolates from a high burden tuberculosis region of North West Pakistan
por: Jabbar, Abdul, et al.
Publicado: (2019)

First Outbreak of NDM-1-Producing Klebsiella pneumoniae ST11 in a Portuguese Hospital Centre during the COVID-19 Pandemic
por: Mendes, Gabriel, et al.
Publicado: (2022)

Machine Learning Predicts Accurately Mycobacterium tuberculosis Drug Resistance From Whole Genome Sequencing Data
por: Deelder, Wouter, et al.
Publicado: (2019)

Genomic and functional portrait of multidrug-resistant, hydrogen sulfide (H(2)S)-producing variants of Escherichia coli
por: Mazumder, Razib, et al.
Publicado: (2023)

Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease
por: Phelan, Jody, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e4c1hr54h0uf3llh40ak7k6c38