A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes

The transcription factor vitamin D receptor (VDR) is the high affinity nuclear target of the biologically active form of vitamin D(3) (1,25(OH)(2)D(3)). In order to identify pure genomic transcriptional effects of 1,25(OH)(2)D(3), we used VDR cistrome, transcriptome and open chromatin data, obtained...

Descripción completa

Detalles Bibliográficos
Autores principales: Warwick, Timothy, Schulz, Marcel H., Günther, Stefan, Gilsbach, Ralf, Neme, Antonio, Carlberg, Carsten, Brandes, Ralf P., Seuter, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985518/
https://www.ncbi.nlm.nih.gov/pubmed/33753848
http://dx.doi.org/10.1038/s41598-021-86032-5

Ejemplares similares

Ejemplares similares