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Exposure to lead and cadmium of the Belgian consumers from ceramic food contact articles
This study was aimed at estimating the intake of lead and cadmium by the Belgian consumers due to the use of ceramic ware. We adopted refined exposure scenarios with respect to migrant concentration, ceramic ware usage, and metal release characteristics. A deterministic estimation was initially perf...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985700/ https://www.ncbi.nlm.nih.gov/pubmed/33777701 http://dx.doi.org/10.1016/j.toxrep.2021.02.015 |
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author | Li, Yan Zhang, Jianqing |
author_facet | Li, Yan Zhang, Jianqing |
author_sort | Li, Yan |
collection | PubMed |
description | This study was aimed at estimating the intake of lead and cadmium by the Belgian consumers due to the use of ceramic ware. We adopted refined exposure scenarios with respect to migrant concentration, ceramic ware usage, and metal release characteristics. A deterministic estimation was initially performed, followed by probabilistic estimation, if the deterministic estimate exceeds toxicological reference values. Based on the reference doses established by the European Food Safety Authority (EFSA), the risk of lead and cadmium exposure was characterized by the margin of exposure (MOE) and the tolerable weekly intake (TWI), respectively. The probabilistic median and 95th percentile intake of lead were 0.02 and 5.77 μg/kg b.w. per day for adults, and 0.07 and 17.3 μg/kg b.w. per day for children. The MOEs for neurotoxicity, nephrotoxicity and cardiovascular effects were 7.1, 27 and 64 for average consumers, and 0.02, 0.1 and 0.3 for high consumers. The deterministic mean and 95th percentile intake of cadmium were 0.026 (7% TWI) and 0.03 (8% TWI) μg/kg b.w. per day for adults, and 0.08 (22 % TWI) and 0.09 (25 % TWI) μg/kg b.w. per day for children. Considering the exposure of the Belgian population from foodstuffs resulted in the exceedance of the TWI by as much as 20-fold. The risk of exposure to lead and cadmium of the Belgian consumers suggests measures, such as lowering the migration limits for ceramic ware, should be taken to minimize the risk. |
format | Online Article Text |
id | pubmed-7985700 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-79857002021-03-25 Exposure to lead and cadmium of the Belgian consumers from ceramic food contact articles Li, Yan Zhang, Jianqing Toxicol Rep Regular Article This study was aimed at estimating the intake of lead and cadmium by the Belgian consumers due to the use of ceramic ware. We adopted refined exposure scenarios with respect to migrant concentration, ceramic ware usage, and metal release characteristics. A deterministic estimation was initially performed, followed by probabilistic estimation, if the deterministic estimate exceeds toxicological reference values. Based on the reference doses established by the European Food Safety Authority (EFSA), the risk of lead and cadmium exposure was characterized by the margin of exposure (MOE) and the tolerable weekly intake (TWI), respectively. The probabilistic median and 95th percentile intake of lead were 0.02 and 5.77 μg/kg b.w. per day for adults, and 0.07 and 17.3 μg/kg b.w. per day for children. The MOEs for neurotoxicity, nephrotoxicity and cardiovascular effects were 7.1, 27 and 64 for average consumers, and 0.02, 0.1 and 0.3 for high consumers. The deterministic mean and 95th percentile intake of cadmium were 0.026 (7% TWI) and 0.03 (8% TWI) μg/kg b.w. per day for adults, and 0.08 (22 % TWI) and 0.09 (25 % TWI) μg/kg b.w. per day for children. Considering the exposure of the Belgian population from foodstuffs resulted in the exceedance of the TWI by as much as 20-fold. The risk of exposure to lead and cadmium of the Belgian consumers suggests measures, such as lowering the migration limits for ceramic ware, should be taken to minimize the risk. Elsevier 2021-02-23 /pmc/articles/PMC7985700/ /pubmed/33777701 http://dx.doi.org/10.1016/j.toxrep.2021.02.015 Text en © 2021 Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Regular Article Li, Yan Zhang, Jianqing Exposure to lead and cadmium of the Belgian consumers from ceramic food contact articles |
title | Exposure to lead and cadmium of the Belgian consumers from ceramic food contact articles |
title_full | Exposure to lead and cadmium of the Belgian consumers from ceramic food contact articles |
title_fullStr | Exposure to lead and cadmium of the Belgian consumers from ceramic food contact articles |
title_full_unstemmed | Exposure to lead and cadmium of the Belgian consumers from ceramic food contact articles |
title_short | Exposure to lead and cadmium of the Belgian consumers from ceramic food contact articles |
title_sort | exposure to lead and cadmium of the belgian consumers from ceramic food contact articles |
topic | Regular Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985700/ https://www.ncbi.nlm.nih.gov/pubmed/33777701 http://dx.doi.org/10.1016/j.toxrep.2021.02.015 |
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