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Digital PCR can provide improved BCR-ABL1 detection in chronic myeloid leukemia patients in deep molecular response and sensitivity of standard quantitative methods using EAC assays
BCR-ABL1 molecular detection using quantitative PCR (qPCR) methods is the golden standard of chronic myeloid leukemia (CML) monitoring. However, due to variable sensitivity of qPCR assays across laboratories, alternative methods are tested. Digital PCR (dPCR) has been suggested as a robust and repro...
Autores principales: | Smitalova, Dagmar, Dvorakova, Dana, Racil, Zdenek, Romzova, Marianna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985703/ https://www.ncbi.nlm.nih.gov/pubmed/33778144 http://dx.doi.org/10.1016/j.plabm.2021.e00210 |
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