Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination

[Image: see text] A formal enone α-arylation is described. This metal-free transformation relies on the I(III)-mediated skeletal reorganization of silyl enol ethers and features mild conditions, good yields, and high stereoselectivities for β-substituted enones.

Detalles Bibliográficos
Autores principales: Martins, Bruna S., Kaiser, Daniel, Bauer, Adriano, Tiefenbrunner, Irmgard, Maulide, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985840/
https://www.ncbi.nlm.nih.gov/pubmed/33635665
http://dx.doi.org/10.1021/acs.orglett.1c00251
Descripción
Sumario:[Image: see text] A formal enone α-arylation is described. This metal-free transformation relies on the I(III)-mediated skeletal reorganization of silyl enol ethers and features mild conditions, good yields, and high stereoselectivities for β-substituted enones.

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