Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination

[Image: see text] A formal enone α-arylation is described. This metal-free transformation relies on the I(III)-mediated skeletal reorganization of silyl enol ethers and features mild conditions, good yields, and high stereoselectivities for β-substituted enones.

Detalles Bibliográficos
Autores principales: Martins, Bruna S., Kaiser, Daniel, Bauer, Adriano, Tiefenbrunner, Irmgard, Maulide, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985840/
https://www.ncbi.nlm.nih.gov/pubmed/33635665
http://dx.doi.org/10.1021/acs.orglett.1c00251
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author Martins, Bruna S.
Kaiser, Daniel
Bauer, Adriano
Tiefenbrunner, Irmgard
Maulide, Nuno
author_facet Martins, Bruna S.
Kaiser, Daniel
Bauer, Adriano
Tiefenbrunner, Irmgard
Maulide, Nuno
author_sort Martins, Bruna S.
collection PubMed
description [Image: see text] A formal enone α-arylation is described. This metal-free transformation relies on the I(III)-mediated skeletal reorganization of silyl enol ethers and features mild conditions, good yields, and high stereoselectivities for β-substituted enones.
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spelling pubmed-79858402021-03-23 Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination Martins, Bruna S. Kaiser, Daniel Bauer, Adriano Tiefenbrunner, Irmgard Maulide, Nuno Org Lett [Image: see text] A formal enone α-arylation is described. This metal-free transformation relies on the I(III)-mediated skeletal reorganization of silyl enol ethers and features mild conditions, good yields, and high stereoselectivities for β-substituted enones. American Chemical Society 2021-02-26 2021-03-19 /pmc/articles/PMC7985840/ /pubmed/33635665 http://dx.doi.org/10.1021/acs.orglett.1c00251 Text en © 2021 The Authors. Published by American Chemical Society Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Martins, Bruna S.
Kaiser, Daniel
Bauer, Adriano
Tiefenbrunner, Irmgard
Maulide, Nuno
Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination
title Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination
title_full Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination
title_fullStr Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination
title_full_unstemmed Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination
title_short Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination
title_sort formal enone α-arylation via i(iii)-mediated aryl migration/elimination
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985840/
https://www.ncbi.nlm.nih.gov/pubmed/33635665
http://dx.doi.org/10.1021/acs.orglett.1c00251
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