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Clinical and obstetric characteristics of pregnant women with Covid-19: A case series study on 26 patients

OBJECTIVE: To evaluate the clinical characteristics and outcomes of pregnant women with Covid-19. MATERIALS AND METHODS: This case series study was performed to investigate demographic, clinical and obstetric characteristics of 26 pregnant women with COVID-19 referring to a university hospital of Ka...

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Autores principales: Abedzadeh-Kalahroudi, Masoumeh, Sehat, Mojtaba, Vahedpour, Zahra, Talebian, Parisa, Haghighi, Akram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985931/
https://www.ncbi.nlm.nih.gov/pubmed/33966728
http://dx.doi.org/10.1016/j.tjog.2021.03.012
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author Abedzadeh-Kalahroudi, Masoumeh
Sehat, Mojtaba
Vahedpour, Zahra
Talebian, Parisa
Haghighi, Akram
author_facet Abedzadeh-Kalahroudi, Masoumeh
Sehat, Mojtaba
Vahedpour, Zahra
Talebian, Parisa
Haghighi, Akram
author_sort Abedzadeh-Kalahroudi, Masoumeh
collection PubMed
description OBJECTIVE: To evaluate the clinical characteristics and outcomes of pregnant women with Covid-19. MATERIALS AND METHODS: This case series study was performed to investigate demographic, clinical and obstetric characteristics of 26 pregnant women with COVID-19 referring to a university hospital of Kashan during the epidemic of COVID-19 (March to May 2020). RESULTS: The mean gestational age of the patients at admission and delivery was 31.8 ± 5.2 and 36.3 ± 3.4 weeks, respectively. The most common symptoms were fever (96.2%) followed by dyspnea and cough (30.8%). The findings of lung CT scan showed abnormalities confirming the pneumonia in 22 patients (84.6%). Cesarean section was performed in 69.2% of the mothers. The most common maternal–fetal outcome was preterm delivery (38%). Two mothers were transferred to the ICU due to deterioration in clinical condition and they underwent mechanical ventilation without any maternal death. The most common neonatal outcomes were prematurity (38%) and low birth weight (34.6%). No cases of confirmed COVID-19 were observed in the neonates. CONCLUSION: Clinical manifestations and laboratory and radiographic findings in pregnant women with COVID-19 are similar to the general population. Common outcomes of pregnancy and delivery in mothers included increased rate of preterm delivery and cesarean section. The most prevalent neonatal outcomes included prematurity and LBW. Careful monitoring of pregnant women with COVID-19 is recommended.
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spelling pubmed-79859312021-03-23 Clinical and obstetric characteristics of pregnant women with Covid-19: A case series study on 26 patients Abedzadeh-Kalahroudi, Masoumeh Sehat, Mojtaba Vahedpour, Zahra Talebian, Parisa Haghighi, Akram Taiwan J Obstet Gynecol Original Article OBJECTIVE: To evaluate the clinical characteristics and outcomes of pregnant women with Covid-19. MATERIALS AND METHODS: This case series study was performed to investigate demographic, clinical and obstetric characteristics of 26 pregnant women with COVID-19 referring to a university hospital of Kashan during the epidemic of COVID-19 (March to May 2020). RESULTS: The mean gestational age of the patients at admission and delivery was 31.8 ± 5.2 and 36.3 ± 3.4 weeks, respectively. The most common symptoms were fever (96.2%) followed by dyspnea and cough (30.8%). The findings of lung CT scan showed abnormalities confirming the pneumonia in 22 patients (84.6%). Cesarean section was performed in 69.2% of the mothers. The most common maternal–fetal outcome was preterm delivery (38%). Two mothers were transferred to the ICU due to deterioration in clinical condition and they underwent mechanical ventilation without any maternal death. The most common neonatal outcomes were prematurity (38%) and low birth weight (34.6%). No cases of confirmed COVID-19 were observed in the neonates. CONCLUSION: Clinical manifestations and laboratory and radiographic findings in pregnant women with COVID-19 are similar to the general population. Common outcomes of pregnancy and delivery in mothers included increased rate of preterm delivery and cesarean section. The most prevalent neonatal outcomes included prematurity and LBW. Careful monitoring of pregnant women with COVID-19 is recommended. Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V. 2021-05 2021-03-23 /pmc/articles/PMC7985931/ /pubmed/33966728 http://dx.doi.org/10.1016/j.tjog.2021.03.012 Text en © 2021 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Article
Abedzadeh-Kalahroudi, Masoumeh
Sehat, Mojtaba
Vahedpour, Zahra
Talebian, Parisa
Haghighi, Akram
Clinical and obstetric characteristics of pregnant women with Covid-19: A case series study on 26 patients
title Clinical and obstetric characteristics of pregnant women with Covid-19: A case series study on 26 patients
title_full Clinical and obstetric characteristics of pregnant women with Covid-19: A case series study on 26 patients
title_fullStr Clinical and obstetric characteristics of pregnant women with Covid-19: A case series study on 26 patients
title_full_unstemmed Clinical and obstetric characteristics of pregnant women with Covid-19: A case series study on 26 patients
title_short Clinical and obstetric characteristics of pregnant women with Covid-19: A case series study on 26 patients
title_sort clinical and obstetric characteristics of pregnant women with covid-19: a case series study on 26 patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985931/
https://www.ncbi.nlm.nih.gov/pubmed/33966728
http://dx.doi.org/10.1016/j.tjog.2021.03.012
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