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Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control

SARS-CoV-2 has a high risk of outbreak in long-term skilled nursing facilities (SNF). Coronavirus disease (COVID-19) has high mortality rates among the elderly with chronic health conditions. Following identification of COVID-19 index case in a SNF, serial point-prevalence was implemented with rever...

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Autores principales: Garibaldi, Pedro M.M., Ferreira, Natasha N., Moraes, Glenda R., Moura, José C., Espósito, Danillo L.A., Volpe, Gustavo J., Calado, Rodrigo T., Fonseca, Benedito A.L., Borges, Marcos C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985963/
https://www.ncbi.nlm.nih.gov/pubmed/33773990
http://dx.doi.org/10.1016/j.bjid.2021.101570
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author Garibaldi, Pedro M.M.
Ferreira, Natasha N.
Moraes, Glenda R.
Moura, José C.
Espósito, Danillo L.A.
Volpe, Gustavo J.
Calado, Rodrigo T.
Fonseca, Benedito A.L.
Borges, Marcos C.
author_facet Garibaldi, Pedro M.M.
Ferreira, Natasha N.
Moraes, Glenda R.
Moura, José C.
Espósito, Danillo L.A.
Volpe, Gustavo J.
Calado, Rodrigo T.
Fonseca, Benedito A.L.
Borges, Marcos C.
author_sort Garibaldi, Pedro M.M.
collection PubMed
description SARS-CoV-2 has a high risk of outbreak in long-term skilled nursing facilities (SNF). Coronavirus disease (COVID-19) has high mortality rates among the elderly with chronic health conditions. Following identification of COVID-19 index case in a SNF, serial point-prevalence was implemented with reverse transcription–polymerase chain reaction (RT-PCR) and immunochromatographic assays. Active surveillance and early isolation of infected patients were implemented. Out of 23 SNF residents and 26 healthcare workers (HCW), 18 (78%) and 12 (46%) tested positive for SARS-CoV-2, respectively. High proportion (38%) of positive patients were asymptomatic and RT-PCR was positive up to six days before symptoms. Five (21.74%) residents were hospitalized with COVID-19, and 2 (9%) died; only 1 (4%) HCW needed to be hospitalized and no staff members died. Active surveillance helped COVID-19 control and management in a SNF. Testing symptomatic individuals only may fail to identify and isolate all persons contributing to transmission. In high-risk elderly, only symptoms screening may not be enough for outbreak control.
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spelling pubmed-79859632021-03-23 Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control Garibaldi, Pedro M.M. Ferreira, Natasha N. Moraes, Glenda R. Moura, José C. Espósito, Danillo L.A. Volpe, Gustavo J. Calado, Rodrigo T. Fonseca, Benedito A.L. Borges, Marcos C. Braz J Infect Dis Original Article SARS-CoV-2 has a high risk of outbreak in long-term skilled nursing facilities (SNF). Coronavirus disease (COVID-19) has high mortality rates among the elderly with chronic health conditions. Following identification of COVID-19 index case in a SNF, serial point-prevalence was implemented with reverse transcription–polymerase chain reaction (RT-PCR) and immunochromatographic assays. Active surveillance and early isolation of infected patients were implemented. Out of 23 SNF residents and 26 healthcare workers (HCW), 18 (78%) and 12 (46%) tested positive for SARS-CoV-2, respectively. High proportion (38%) of positive patients were asymptomatic and RT-PCR was positive up to six days before symptoms. Five (21.74%) residents were hospitalized with COVID-19, and 2 (9%) died; only 1 (4%) HCW needed to be hospitalized and no staff members died. Active surveillance helped COVID-19 control and management in a SNF. Testing symptomatic individuals only may fail to identify and isolate all persons contributing to transmission. In high-risk elderly, only symptoms screening may not be enough for outbreak control. Elsevier 2021-03-23 /pmc/articles/PMC7985963/ /pubmed/33773990 http://dx.doi.org/10.1016/j.bjid.2021.101570 Text en © 2021 Sociedade Brasileira de Infectologia. Published by Elsevier España, S.L.U. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Garibaldi, Pedro M.M.
Ferreira, Natasha N.
Moraes, Glenda R.
Moura, José C.
Espósito, Danillo L.A.
Volpe, Gustavo J.
Calado, Rodrigo T.
Fonseca, Benedito A.L.
Borges, Marcos C.
Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control
title Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control
title_full Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control
title_fullStr Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control
title_full_unstemmed Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control
title_short Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control
title_sort efficacy of covid-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985963/
https://www.ncbi.nlm.nih.gov/pubmed/33773990
http://dx.doi.org/10.1016/j.bjid.2021.101570
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