London Dispersion Interactions Rather than Steric Hindrance Determine the Enantioselectivity of the Corey–Bakshi–Shibata Reduction

The well‐known Corey–Bakshi–Shibata (CBS) reduction is a powerful method for the asymmetric synthesis of alcohols from prochiral ketones, often featuring high yields and excellent selectivities. While steric repulsion has been regarded as the key director of the observed high enantioselectivity for...

Descripción completa

Detalles Bibliográficos
Autores principales: Eschmann, Christian, Song, Lijuan, Schreiner, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986100/
https://www.ncbi.nlm.nih.gov/pubmed/33205853
http://dx.doi.org/10.1002/anie.202012760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986100/
https://www.ncbi.nlm.nih.gov/pubmed/33205853
http://dx.doi.org/10.1002/anie.202012760

Ejemplares similares