Oncometabolite L‐2‐hydroxyglurate directly induces vasculogenic mimicry through PHLDB2 in renal cell carcinoma

Metabolism reprograming is a hallmark of cancer and plays an important role in tumor progression. The aberrant metabolism in renal cell carcinoma (RCC) leads to accumulation of the oncometabolite l‐2‐hydroxyglurate (L‐2HG). L‐2HG has been reported to inhibit the activity of some α‐ketoglutarate‐depe...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Wang, Liya, Zheng, Qiming, Lu, Zeyi, Chen, Yuanlei, Shen, Danyang, Xue, Dingwei, Jiang, Minxiao, Ding, Lifeng, Zhang, Jie, Wu, Haiyang, Xia, Liqun, Qian, Jun, Li, Gonghui, Lu, Jieyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Tumor Immunology and Microenvironment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986127/
https://www.ncbi.nlm.nih.gov/pubmed/33320958
http://dx.doi.org/10.1002/ijc.33435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986127/
https://www.ncbi.nlm.nih.gov/pubmed/33320958
http://dx.doi.org/10.1002/ijc.33435

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