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4‐1BB costimulation promotes bystander activation of human CD8 T cells

Costimulatory signals potently promote T‐cell proliferation and effector function. Agonistic antibodies targeting costimulatory receptors of the TNFR family, such as 4‐1BB and CD27, have entered clinical trials in cancer patients. Currently there is limited information how costimulatory signals regu...

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Detalles Bibliográficos
Autores principales:	Reithofer, Manuel, Rosskopf, Sandra, Leitner, Judith, Battin, Claire, Bohle, Barbara, Steinberger, Peter, Jahn‐Schmid, Beatrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Immunomodulation and immune therapies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986150/ https://www.ncbi.nlm.nih.gov/pubmed/33180337 http://dx.doi.org/10.1002/eji.202048762

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