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4‐1BB costimulation promotes bystander activation of human CD8 T cells
Costimulatory signals potently promote T‐cell proliferation and effector function. Agonistic antibodies targeting costimulatory receptors of the TNFR family, such as 4‐1BB and CD27, have entered clinical trials in cancer patients. Currently there is limited information how costimulatory signals regu...
Autores principales: | Reithofer, Manuel, Rosskopf, Sandra, Leitner, Judith, Battin, Claire, Bohle, Barbara, Steinberger, Peter, Jahn‐Schmid, Beatrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986150/ https://www.ncbi.nlm.nih.gov/pubmed/33180337 http://dx.doi.org/10.1002/eji.202048762 |
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