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Perampanel and pregnancy

OBJECTIVE: The objective was to summarize pregnancy and fetal/postnatal outcomes following maternal perampanel exposure using preclinical and clinical data, and to use physiologically based pharmacokinetic (PBPK) modeling to improve understanding of perampanel pharmacokinetics (PK) during pregnancy....

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Detalles Bibliográficos
Autores principales: Vazquez, Blanca, Tomson, Torbjörn, Dobrinsky, Cindy, Schuck, Edgar, O’Brien, Terence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986165/
https://www.ncbi.nlm.nih.gov/pubmed/33666943
http://dx.doi.org/10.1111/epi.16821

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