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Systemic review of CNS involvement and its manifestations in SARS-CoV2 positive patients
Coronavirus is known to cause various systemic infections both in human and animal which are mostly mild in nature. However, recent years have seen major pandemics caused by coronavirus which are very invasive and virulent in nature. The recent SARS-CoV2 is a new addition to this list of coronavirus...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986314/ https://www.ncbi.nlm.nih.gov/pubmed/34020214 http://dx.doi.org/10.1016/j.jiph.2021.03.005 |
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author | Yadav, Ramakant Srivastava, Dhiraj Kumar Bajpai, Prashant Kumar Kumar, Raj |
author_facet | Yadav, Ramakant Srivastava, Dhiraj Kumar Bajpai, Prashant Kumar Kumar, Raj |
author_sort | Yadav, Ramakant |
collection | PubMed |
description | Coronavirus is known to cause various systemic infections both in human and animal which are mostly mild in nature. However, recent years have seen major pandemics caused by coronavirus which are very invasive and virulent in nature. The recent SARS-CoV2 is a new addition to this list of coronavirus pandemics. So the present study was done to systematically review the CNS involvement and its manifestations in SARS-CoV2 positive patients. Systemic review of article published between 1st Dec 2019 to 31st July 2020 searched through web-based database of MEDLINE (Pubmed) and Google scholar using following keywords “COVID -19” OR “CORONAVIRUS” OR “SARS-CoV2” AND “NEUROLOGICAL” OR “CNS” OR “BRAIN”. Using the steps of systemic review eight article were selected for qualitative analysis. Majority of these article were reporting neurological symptoms among patients admitted in different wards along with others general symptoms. None of the study was specifically devoted to study the neurological manifestations and complications in SARS-CoV2 positive patients. The present study concludes that there is a scarcity of good quality research which attempts to establish the role of SARS-CoV2 infection in CNS and its manifestations. However, there are evidences that CNS involvement is present in majority of the patients. Proper documentation of theses involvement and indentification of these into mild, moderate and severe infection will help in early identification and treatment of these patients. |
format | Online Article Text |
id | pubmed-7986314 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79863142021-03-24 Systemic review of CNS involvement and its manifestations in SARS-CoV2 positive patients Yadav, Ramakant Srivastava, Dhiraj Kumar Bajpai, Prashant Kumar Kumar, Raj J Infect Public Health Article Coronavirus is known to cause various systemic infections both in human and animal which are mostly mild in nature. However, recent years have seen major pandemics caused by coronavirus which are very invasive and virulent in nature. The recent SARS-CoV2 is a new addition to this list of coronavirus pandemics. So the present study was done to systematically review the CNS involvement and its manifestations in SARS-CoV2 positive patients. Systemic review of article published between 1st Dec 2019 to 31st July 2020 searched through web-based database of MEDLINE (Pubmed) and Google scholar using following keywords “COVID -19” OR “CORONAVIRUS” OR “SARS-CoV2” AND “NEUROLOGICAL” OR “CNS” OR “BRAIN”. Using the steps of systemic review eight article were selected for qualitative analysis. Majority of these article were reporting neurological symptoms among patients admitted in different wards along with others general symptoms. None of the study was specifically devoted to study the neurological manifestations and complications in SARS-CoV2 positive patients. The present study concludes that there is a scarcity of good quality research which attempts to establish the role of SARS-CoV2 infection in CNS and its manifestations. However, there are evidences that CNS involvement is present in majority of the patients. Proper documentation of theses involvement and indentification of these into mild, moderate and severe infection will help in early identification and treatment of these patients. Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. 2021-06 2021-03-23 /pmc/articles/PMC7986314/ /pubmed/34020214 http://dx.doi.org/10.1016/j.jiph.2021.03.005 Text en © 2021 Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Yadav, Ramakant Srivastava, Dhiraj Kumar Bajpai, Prashant Kumar Kumar, Raj Systemic review of CNS involvement and its manifestations in SARS-CoV2 positive patients |
title | Systemic review of CNS involvement and its manifestations in SARS-CoV2 positive patients |
title_full | Systemic review of CNS involvement and its manifestations in SARS-CoV2 positive patients |
title_fullStr | Systemic review of CNS involvement and its manifestations in SARS-CoV2 positive patients |
title_full_unstemmed | Systemic review of CNS involvement and its manifestations in SARS-CoV2 positive patients |
title_short | Systemic review of CNS involvement and its manifestations in SARS-CoV2 positive patients |
title_sort | systemic review of cns involvement and its manifestations in sars-cov2 positive patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986314/ https://www.ncbi.nlm.nih.gov/pubmed/34020214 http://dx.doi.org/10.1016/j.jiph.2021.03.005 |
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