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Establishment of an in vitro model for analyzing mitochondrial ultrastructure in PRKN-mutated patient iPSC-derived dopaminergic neurons

Mitochondrial structural changes are associated with the regulation of mitochondrial function, apoptosis, and neurodegenerative diseases. PRKN is known to be involved with various mechanisms of mitochondrial quality control including mitochondrial structural changes. Parkinson’s disease (PD) with PR...

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Detalles Bibliográficos
Autores principales:	Yokota, Mutsumi, Kakuta, Soichiro, Shiga, Takahiro, Ishikawa, Kei-ichi, Okano, Hideyuki, Hattori, Nobutaka, Akamatsu, Wado, Koike, Masato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986497/ https://www.ncbi.nlm.nih.gov/pubmed/33757554 http://dx.doi.org/10.1186/s13041-021-00771-0

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