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Experiences with IL-1 blockade in systemic juvenile idiopathic arthritis – data from the German AID-registry
BACKGROUND: Systemic juvenile idiopathic arthritis (sJIA) is a complex disease with dysregulation of the innate immune system driven by cytokines. A major role is ascribed to interleukin-1β (IL-1β), supporting the autoinflammatory character of the disease and offering an effective blocking mechanism...
Autores principales: | Lainka, Elke, Baehr, Melanie, Raszka, Bernadette, Haas, Johannes-Peter, Hügle, Boris, Fischer, Nadine, Foell, Dirk, Hinze, Claas, Weissbarth-Riedel, Elisabeth, Kallinich, Tilmann, Horneff, Gerd, Windschall, Daniel, Lilienthal, Eggert, Niehues, Tim, Neudorf, Ulrich, Berendes, Rainer, Küster, Rolf-Michael, Oommen, Prasad Thomas, Rietschel, Christoph, Lutz, Thomas, Weller-Heinemann, Frank, Tenbrock, Klaus, Heubner, Georg Leonhard, Klotsche, Jens, Wittkowski, Helmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986520/ https://www.ncbi.nlm.nih.gov/pubmed/33752669 http://dx.doi.org/10.1186/s12969-021-00510-8 |
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