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In Vivo Assembly of Artificial Metalloenzymes and Application in Whole‐Cell Biocatalysis

We report the supramolecular assembly of artificial metalloenzymes (ArMs), based on the Lactococcal multidrug resistance regulator (LmrR) and an exogeneous copper(II)–phenanthroline complex, in the cytoplasm of E. coli cells. A combination of catalysis, cell‐fractionation, and inhibitor experiments,...

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Detalles Bibliográficos
Autores principales: Chordia, Shreyans, Narasimhan, Siddarth, Lucini Paioni, Alessandra, Baldus, Marc, Roelfes, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986609/
https://www.ncbi.nlm.nih.gov/pubmed/33428816
http://dx.doi.org/10.1002/anie.202014771

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