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Polymeric Pathogen-Like Particles-Based Combination Adjuvants Elicit Potent Mucosal T Cell Immunity to Influenza A Virus
Eliciting durable and protective T cell-mediated immunity in the respiratory mucosa remains a significant challenge. Polylactic-co-glycolic acid (PLGA)-based cationic pathogen-like particles (PLPs) loaded with TLR agonists mimic biophysical properties of microbes and hence, simulate pathogen-pattern...
Autores principales: | Kingstad-Bakke, Brock, Toy, Randall, Lee, Woojong, Pradhan, Pallab, Vogel, Gabriela, Marinaik, Chandranaik B., Larsen, Autumn, Gates, Daisy, Luu, Tracy, Pandey, Bhawana, Kawaoka, Yoshihoro, Roy, Krishnendu, Suresh, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986715/ https://www.ncbi.nlm.nih.gov/pubmed/33767689 http://dx.doi.org/10.3389/fimmu.2020.559382 |
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