Cargando…

Primary Borderline Mucinous Testicular Tumor: A Case Report and Literature Review

Primary mucinous tumors of the testis and paratestis are very rare, with only 29 reported cases detected in a PubMed search. The histopathological characteristics of primary testicular mucinous tumors are similar to their ovarian counterparts, and the diagnosis and naming criteria refer to the crite...

Descripción completa

Detalles Bibliográficos
Autores principales: Hao, Changjuan, Kang, Chunsong, Kang, Xiaoyan, Yu, Zhuanzhuan, Li, Tingting, Xue, Jiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986722/
https://www.ncbi.nlm.nih.gov/pubmed/33767975
http://dx.doi.org/10.3389/fonc.2020.619774
_version_ 1783668498935840768
author Hao, Changjuan
Kang, Chunsong
Kang, Xiaoyan
Yu, Zhuanzhuan
Li, Tingting
Xue, Jiping
author_facet Hao, Changjuan
Kang, Chunsong
Kang, Xiaoyan
Yu, Zhuanzhuan
Li, Tingting
Xue, Jiping
author_sort Hao, Changjuan
collection PubMed
description Primary mucinous tumors of the testis and paratestis are very rare, with only 29 reported cases detected in a PubMed search. The histopathological characteristics of primary testicular mucinous tumors are similar to their ovarian counterparts, and the diagnosis and naming criteria refer to the criteria for female ovarian mucinous tumors. However, the clinical and imaging features of primary testicular mucinous tumors are poorly understood, and they are thus frequently undiagnosed or misdiagnosed. We present the case of a patient with a primary testicular mucinous tumor. A 52-year-old man presented with a 1-year history of painless enlargement of the left scrotum. Ultrasound examination revealed a cystic mass in the left testis, with viscous fluid areas and calcified spots, irregular solid bulges on the cyst wall, and a small blood supply. Serum alpha-fetoprotein, β-human chorionic gonadotropin, lactate dehydrogenase, renal function, inflammatory markers, and routine urine and blood examinations were all normal. The patient underwent radical resection of the left testis. Postoperative pathology showed a multilocular cystic mass, with the inner wall of the sac lined with mucous columnar epithelial cells, some with mild nuclear atypia, and no interstitial infiltration. The pathological diagnosis was testicular mucinous tumor. Postoperative abdominal and pelvic computed tomography, colonoscopy, and gastroscopy showed no suspicious lesions. The final diagnosis was primary testicular borderline mucinous tumor. The patient underwent postoperative follow-up examinations once a year for 4 years. Serum tumor markers, scrotal ultrasound, abdominal and pelvic computed tomography scans, and colonoscopy and gastroscopy revealed no evidence of metastases or other primary adenocarcinoma. This case highlights the clinical and imaging characteristics of primary testicular mucinous tumors, which might aid their differential diagnosis.
format Online
Article
Text
id pubmed-7986722
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-79867222021-03-24 Primary Borderline Mucinous Testicular Tumor: A Case Report and Literature Review Hao, Changjuan Kang, Chunsong Kang, Xiaoyan Yu, Zhuanzhuan Li, Tingting Xue, Jiping Front Oncol Oncology Primary mucinous tumors of the testis and paratestis are very rare, with only 29 reported cases detected in a PubMed search. The histopathological characteristics of primary testicular mucinous tumors are similar to their ovarian counterparts, and the diagnosis and naming criteria refer to the criteria for female ovarian mucinous tumors. However, the clinical and imaging features of primary testicular mucinous tumors are poorly understood, and they are thus frequently undiagnosed or misdiagnosed. We present the case of a patient with a primary testicular mucinous tumor. A 52-year-old man presented with a 1-year history of painless enlargement of the left scrotum. Ultrasound examination revealed a cystic mass in the left testis, with viscous fluid areas and calcified spots, irregular solid bulges on the cyst wall, and a small blood supply. Serum alpha-fetoprotein, β-human chorionic gonadotropin, lactate dehydrogenase, renal function, inflammatory markers, and routine urine and blood examinations were all normal. The patient underwent radical resection of the left testis. Postoperative pathology showed a multilocular cystic mass, with the inner wall of the sac lined with mucous columnar epithelial cells, some with mild nuclear atypia, and no interstitial infiltration. The pathological diagnosis was testicular mucinous tumor. Postoperative abdominal and pelvic computed tomography, colonoscopy, and gastroscopy showed no suspicious lesions. The final diagnosis was primary testicular borderline mucinous tumor. The patient underwent postoperative follow-up examinations once a year for 4 years. Serum tumor markers, scrotal ultrasound, abdominal and pelvic computed tomography scans, and colonoscopy and gastroscopy revealed no evidence of metastases or other primary adenocarcinoma. This case highlights the clinical and imaging characteristics of primary testicular mucinous tumors, which might aid their differential diagnosis. Frontiers Media S.A. 2021-03-09 /pmc/articles/PMC7986722/ /pubmed/33767975 http://dx.doi.org/10.3389/fonc.2020.619774 Text en Copyright © 2021 Hao, Kang, Kang, Yu, Li and Xue http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Hao, Changjuan
Kang, Chunsong
Kang, Xiaoyan
Yu, Zhuanzhuan
Li, Tingting
Xue, Jiping
Primary Borderline Mucinous Testicular Tumor: A Case Report and Literature Review
title Primary Borderline Mucinous Testicular Tumor: A Case Report and Literature Review
title_full Primary Borderline Mucinous Testicular Tumor: A Case Report and Literature Review
title_fullStr Primary Borderline Mucinous Testicular Tumor: A Case Report and Literature Review
title_full_unstemmed Primary Borderline Mucinous Testicular Tumor: A Case Report and Literature Review
title_short Primary Borderline Mucinous Testicular Tumor: A Case Report and Literature Review
title_sort primary borderline mucinous testicular tumor: a case report and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986722/
https://www.ncbi.nlm.nih.gov/pubmed/33767975
http://dx.doi.org/10.3389/fonc.2020.619774
work_keys_str_mv AT haochangjuan primaryborderlinemucinoustesticulartumoracasereportandliteraturereview
AT kangchunsong primaryborderlinemucinoustesticulartumoracasereportandliteraturereview
AT kangxiaoyan primaryborderlinemucinoustesticulartumoracasereportandliteraturereview
AT yuzhuanzhuan primaryborderlinemucinoustesticulartumoracasereportandliteraturereview
AT litingting primaryborderlinemucinoustesticulartumoracasereportandliteraturereview
AT xuejiping primaryborderlinemucinoustesticulartumoracasereportandliteraturereview