3D hydrogels reveal medulloblastoma subgroup differences and identify extracellular matrix subtypes that predict patient outcome

Medulloblastoma (MB) is the most common malignant brain tumour in children and is subdivided into four subgroups: WNT, SHH, Group 3, and Group 4. These molecular subgroups differ in their metastasis patterns and related prognosis rates. Conventional 2D cell culture methods fail to recapitulate these...

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Detalles Bibliográficos
Autores principales: Linke, Franziska, Aldighieri, Macha, Lourdusamy, Anbarasu, Grabowska, Anna M, Stolnik, Snow, Kerr, Ian D, Merry, Catherine LR, Coyle, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986745/
https://www.ncbi.nlm.nih.gov/pubmed/33206391
http://dx.doi.org/10.1002/path.5591

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