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Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche
BACKGROUND: Multiple myeloma (MM) remains an incurable disease and oncolytic viruses offer a well-tolerated addition to the therapeutic arsenal. Oncolytic reovirus has progressed to phase I clinical trials and its direct lytic potential has been extensively studied. However, to date, the role for re...
Autores principales: | Müller, Louise M E, Migneco, Gemma, Scott, Gina B, Down, Jenny, King, Sancha, Askar, Basem, Jennings, Victoria, Oyajobi, Babatunde, Scott, Karen, West, Emma, Ralph, Christy, Samson, Adel, Ilett, Elizabeth J, Muthana, Munitta, Coffey, Matt, Melcher, Alan, Parrish, Christopher, Cook, Gordon, Lawson, Michelle, Errington-Mais, Fiona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986878/ https://www.ncbi.nlm.nih.gov/pubmed/33741729 http://dx.doi.org/10.1136/jitc-2020-001803 |
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