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Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche

BACKGROUND: Multiple myeloma (MM) remains an incurable disease and oncolytic viruses offer a well-tolerated addition to the therapeutic arsenal. Oncolytic reovirus has progressed to phase I clinical trials and its direct lytic potential has been extensively studied. However, to date, the role for re...

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Detalles Bibliográficos
Autores principales: Müller, Louise M E, Migneco, Gemma, Scott, Gina B, Down, Jenny, King, Sancha, Askar, Basem, Jennings, Victoria, Oyajobi, Babatunde, Scott, Karen, West, Emma, Ralph, Christy, Samson, Adel, Ilett, Elizabeth J, Muthana, Munitta, Coffey, Matt, Melcher, Alan, Parrish, Christopher, Cook, Gordon, Lawson, Michelle, Errington-Mais, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986878/
https://www.ncbi.nlm.nih.gov/pubmed/33741729
http://dx.doi.org/10.1136/jitc-2020-001803

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