Cargando…
PAKC: A novel panel of HLA class I antigen presentation machinery knockout cells from the same genetic origin
A single model system for integrative studies on multiple facets of antigen presentation is lacking. PAKC is a novel panel of ten cell lines knocked out for individual components of the HLA class I antigen presentation pathway. PAKC will accelerate HLA‐I research in the fields of oncology, infectiol...
Autores principales: | de Waard, Antonius A., Verkerk, Tamara, Jongsma, Marlieke L. M., Hoefakker, Kelly, Sethumadhavan, Sunesh, Gerke, Carolin, Bliss, Sophie, Kong, Xiangrui, Janssen, George M. C., de Ru, Arnoud H., Claas, Frans H. J., Mulder, Arend, Tampé, Robert, van Veelen, Peter A., Halenius, Anne, Spaapen, Robbert M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986913/ https://www.ncbi.nlm.nih.gov/pubmed/33275281 http://dx.doi.org/10.1002/eji.202048599 |
Ejemplares similares
-
Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens
por: de Waard, Antonius A., et al.
Publicado: (2021) -
Viral immune evasins impact antigen presentation by allele-specific trapping of MHC I at the peptide-loading complex
por: Sethumadhavan, Sunesh, et al.
Publicado: (2022) -
Identification of potential immunotherapeutic targets in antigen presentation and costimulation networks
por: Spaapen, Robbert, et al.
Publicado: (2014) -
The Role of Glycosphingolipids in Immune Cell Functions
por: Zhang, Tao, et al.
Publicado: (2019) -
An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport
por: Jongsma, Marlieke L.M., et al.
Publicado: (2016)