Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

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Understanding the ability of SARS-CoV-2 vaccine-elicited antibodies to neutralize and protect against emerging variants of concern and other sarbecoviruses is key for guiding vaccine development decisions and public health policies. We show that a clinical stage multivalent SARS-CoV-2 receptor-bindi...

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Detalles Bibliográficos
Autores principales: Walls, Alexandra C., Miranda, Marcos C., Pham, Minh N., Schäfer, Alexandra, Greaney, Allison, Arunachalam, Prabhu S., Navarro, Mary-Jane, Tortorici, M. Alejandra, Rogers, Kenneth, O’Connor, Megan A., Shireff, Lisa, Ferrell, Douglas E., Brunette, Natalie, Kepl, Elizabeth, Bowen, John, Zepeda, Samantha K., Starr, Tyler, Hsieh, Ching-Lin, Fiala, Brooke, Wrenn, Samuel, Pettie, Deleah, Sydeman, Claire, Johnson, Max, Blackstone, Alyssa, Ravichandran, Rashmi, Ogohara, Cassandra, Carter, Lauren, Tilles, Sasha W., Rappuoli, Rino, O’Hagan, Derek T., Van Der Most, Robbert, Van Voorhis, Wesley C., McLellan, Jason S., Kleanthous, Harry, Sheahan, Timothy P., Fuller, Deborah H., Villinger, Francois, Bloom, Jesse, Pulendran, Bali, Baric, Ralph, King, Neil, Veesler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986998/
https://www.ncbi.nlm.nih.gov/pubmed/33758839
http://dx.doi.org/10.1101/2021.03.15.435528
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