Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation

We identified a novel SARS-CoV-2 variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples from 44 counties in California. Named B.1.427/B.1.429 to denote its 2 lineages, the variant emerged around May 2020 and increased from 0% to >50% of sequenced cases from September...

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Detalles Bibliográficos
Autores principales: Deng, Xianding, Garcia-Knight, Miguel A, Khalid, Mir M., Servellita, Venice, Wang, Candace, Morris, Mary Kate, Sotomayor-González, Alicia, Glasner, Dustin R, Reyes, Kevin R, Gliwa, Amelia S., Reddy, Nikitha P., Martin, Claudia Sanchez San, Federman, Scot, Cheng, Jing, Balcerek, Joanna, Taylor, Jordan, Streithorst, Jessica A, Miller, Steve, Kumar, G. Renuka, Sreekumar, Bharath, Chen, Pei-Yi, Schulze-Gahmen, Ursula, Taha, Taha Y., Hayashi, Jennifer, Simoneau, Camille R., McMahon, Sarah, Lidsky, Peter V., Xiao, Yinghong, Hemarajata, Peera, Green, Nicole M., Espinosa, Alex, Kath, Chantha, Haw, Monica, Bell, John, Hacker, Jill K., Hanson, Carl, Wadford, Debra A., Anaya, Carlos, Ferguson, Donna, Lareau, Liana F., Frankino, Phillip A., Shivram, Haridha, Wyman, Stacia K., Ott, Melanie, Andino, Raul, Chiu, Charles Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987058/
https://www.ncbi.nlm.nih.gov/pubmed/33758899
http://dx.doi.org/10.1101/2021.03.07.21252647

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