Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults

Magnitude of SARS-CoV-2 virus exposure may contribute to symptom severity. In a sample of seropositive adults (n=1101), we found that individuals who lived with a known COVID-19 case exhibited greater symptom severity and IgG concentrations compared to individuals who were seropositive but did not l...

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Autores principales: Schrock, Joshua M., Ryan, Daniel T., Saber, Rana, Benbow, Nanette, Vaught, Lauren A., Reiser, Nina, Velez, Matthew P., Hsieh, Ryan, Newcomb, Michael, Demonbreun, Alexis R., Mustanski, Brian, McNally, Elizabeth M., D’Aquila, Richard, McDade, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987062/
https://www.ncbi.nlm.nih.gov/pubmed/33758903
http://dx.doi.org/10.1101/2021.03.11.21253421
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author Schrock, Joshua M.
Ryan, Daniel T.
Saber, Rana
Benbow, Nanette
Vaught, Lauren A.
Reiser, Nina
Velez, Matthew P.
Hsieh, Ryan
Newcomb, Michael
Demonbreun, Alexis R.
Mustanski, Brian
McNally, Elizabeth M.
D’Aquila, Richard
McDade, Thomas W.
author_facet Schrock, Joshua M.
Ryan, Daniel T.
Saber, Rana
Benbow, Nanette
Vaught, Lauren A.
Reiser, Nina
Velez, Matthew P.
Hsieh, Ryan
Newcomb, Michael
Demonbreun, Alexis R.
Mustanski, Brian
McNally, Elizabeth M.
D’Aquila, Richard
McDade, Thomas W.
author_sort Schrock, Joshua M.
collection PubMed
description Magnitude of SARS-CoV-2 virus exposure may contribute to symptom severity. In a sample of seropositive adults (n=1101), we found that individuals who lived with a known COVID-19 case exhibited greater symptom severity and IgG concentrations compared to individuals who were seropositive but did not live with a known case (P<0.0001).
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spelling pubmed-79870622021-03-24 Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults Schrock, Joshua M. Ryan, Daniel T. Saber, Rana Benbow, Nanette Vaught, Lauren A. Reiser, Nina Velez, Matthew P. Hsieh, Ryan Newcomb, Michael Demonbreun, Alexis R. Mustanski, Brian McNally, Elizabeth M. D’Aquila, Richard McDade, Thomas W. medRxiv Article Magnitude of SARS-CoV-2 virus exposure may contribute to symptom severity. In a sample of seropositive adults (n=1101), we found that individuals who lived with a known COVID-19 case exhibited greater symptom severity and IgG concentrations compared to individuals who were seropositive but did not live with a known case (P<0.0001). Cold Spring Harbor Laboratory 2021-03-12 /pmc/articles/PMC7987062/ /pubmed/33758903 http://dx.doi.org/10.1101/2021.03.11.21253421 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator.
spellingShingle Article
Schrock, Joshua M.
Ryan, Daniel T.
Saber, Rana
Benbow, Nanette
Vaught, Lauren A.
Reiser, Nina
Velez, Matthew P.
Hsieh, Ryan
Newcomb, Michael
Demonbreun, Alexis R.
Mustanski, Brian
McNally, Elizabeth M.
D’Aquila, Richard
McDade, Thomas W.
Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults
title Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults
title_full Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults
title_fullStr Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults
title_full_unstemmed Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults
title_short Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults
title_sort exposure to sars-cov-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987062/
https://www.ncbi.nlm.nih.gov/pubmed/33758903
http://dx.doi.org/10.1101/2021.03.11.21253421
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