Lung gene expression and single cell analyses reveal two subsets of idiopathic pulmonary fibrosis (IPF) patients associated with different pathogenic mechanisms

Idiopathic pulmonary fibrosis is a progressive and debilitating lung disease with large unmet medical need and few treatment options. We describe an analysis connecting single cell gene expression with bulk gene expression-based subsetting of patient cohorts to identify IPF patient subsets with diff...

Descripción completa

Detalles Bibliográficos
Autores principales: Karman, Jozsef, Wang, Jing, Bodea, Corneliu, Cao, Sherry, Levesque, Marc C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987152/
https://www.ncbi.nlm.nih.gov/pubmed/33755690
http://dx.doi.org/10.1371/journal.pone.0248889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987152/
https://www.ncbi.nlm.nih.gov/pubmed/33755690
http://dx.doi.org/10.1371/journal.pone.0248889

Ejemplares similares