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Lung gene expression and single cell analyses reveal two subsets of idiopathic pulmonary fibrosis (IPF) patients associated with different pathogenic mechanisms
Idiopathic pulmonary fibrosis is a progressive and debilitating lung disease with large unmet medical need and few treatment options. We describe an analysis connecting single cell gene expression with bulk gene expression-based subsetting of patient cohorts to identify IPF patient subsets with diff...
Autores principales: | Karman, Jozsef, Wang, Jing, Bodea, Corneliu, Cao, Sherry, Levesque, Marc C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987152/ https://www.ncbi.nlm.nih.gov/pubmed/33755690 http://dx.doi.org/10.1371/journal.pone.0248889 |
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