Cargando…

The β3 Adrenergic Receptor Agonist CL316243 Ameliorates the Metabolic Abnormalities of High-Fat Diet-Fed Rats by Activating AMPK/PGC-1α Signaling in Skeletal Muscle

PURPOSE: Skeletal muscle has a major influence on whole-body metabolic homeostasis. In the present study, we aimed to determine the metabolic effects of the β3 adrenergic receptor agonist CL316243 (CL) in the skeletal muscle of high-fat diet-fed rats. METHODS: Sprague-Dawley rats were randomly alloc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ding, Li-Na, Cheng, Ya, Xu, Lu-Yao, Zhou, Le-Quan, Guan, Li, Liu, Hai-Mei, Zhang, Ya-Xing, Li, Run-Mei, Xu, Jin-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987271/ https://www.ncbi.nlm.nih.gov/pubmed/33776460 http://dx.doi.org/10.2147/DMSO.S297351

Ejemplares similares

CL316,243, a β3-adrenergic receptor agonist, induces muscle hypertrophy and increased strength
por: Puzzo, Daniela, et al.
Publicado: (2016)

Apparent histological changes of adipocytes after treatment with CL 316,243, a β-3-adrenergic receptor agonist
por: Ghorbani, Masoud, et al.
Publicado: (2015)

Anti-obesity and metabolic efficacy of the β3-adrenergic agonist, CL316243, in mice at thermoneutrality compared to 22°C
por: Xiao, Cuiying, et al.
Publicado: (2015)

Anti Diabetic effect of CL 316,243 (A β3-Adrenergic Agonist) by Down Regulation of Tumour Necrosis Factor (TNF-α) Expression
por: Ghorbani, Masoud, et al.
Publicado: (2012)

The beta-3 adrenergic agonist (CL-316,243) restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice
por: Kumar, Amit, et al.
Publicado: (2015)

Erchen Decoction Ameliorates the Metabolic Abnormalities of High-Fat Diet-Fed Rats
por: Cheng, Ya, et al.
Publicado: (2022)

Comparative Transcriptome Profiling of Cold Exposure and β3-AR Agonist CL316,243-Induced Browning of White Fat
por: Li, Yu, et al.
Publicado: (2021)

The glucose lowering effects of CL 316,243 dissipate with repeated use and are rescued bycilostamide
por: Medak, Kyle D., et al.
Publicado: (2022)

Effects of Combined Oxytocin and Beta-3 Receptor Agonist (CL 316243) Treatment on Body Weight and Adiposity in Male Diet-Induced Obese Rats
por: Edwards, Melise M., et al.
Publicado: (2021)

Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis
por: Zhu, Yi, et al.
Publicado: (2021)

An Additive Effect of Promoting Thermogenic Gene Expression in Mice Adipose-Derived Stromal Vascular Cells by Combination of Rosiglitazone and CL316,243
por: Li, You-Lei, et al.
Publicado: (2017)

Investigation of the skeletal muscle transcriptome in lambs fed β adrenergic agonists and subjected to heat stress for 21 d()
por: Kubik, Rachel M, et al.
Publicado: (2018)

Broccoli-Derived Glucoraphanin Activates AMPK/PGC1α/NRF2 Pathway and Ameliorates Dextran-Sulphate-Sodium-Induced Colitis in Mice
por: Tian, Qiyu, et al.
Publicado: (2022)

Time since menopause and skeletal muscle estrogen receptors, PGC-1α, and AMPK
por: Park, Young-Min, et al.
Publicado: (2017)

Paeoniflorin Ameliorates Skeletal Muscle Atrophy in Chronic Kidney Disease via AMPK/SIRT1/PGC-1α-Mediated Oxidative Stress and Mitochondrial Dysfunction
por: Li, Qiang, et al.
Publicado: (2022)

Welfare traits of Bos indicus cattle castrated immunologically and fed beta-adrenergic agonists
por: Martello, Luciane Silva, et al.
Publicado: (2021)

Beta-Adrenergic Agonists
por: Barisione, Giovanni, et al.
Publicado: (2010)

Activation of AMPK-PGC-1α pathway ameliorates peritoneal dialysis related peritoneal fibrosis in mice by enhancing mitochondrial biogenesis
por: Wu, Jun, et al.
Publicado: (2022)

Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle
por: Palacios, Orsolya M., et al.
Publicado: (2009)

FGF19 protects skeletal muscle against obesity‐induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT‐1/PGC‐α pathway
por: Guo, Ai, et al.
Publicado: (2021)

Myostatin Knockout Affects Mitochondrial Function by Inhibiting the AMPK/SIRT1/PGC1α Pathway in Skeletal Muscle
por: Gu, Mingjuan, et al.
Publicado: (2022)

Skeletal muscle insulin resistance in hamsters with diabetes developed from obesity is involved in abnormal skeletal muscle LXR, PPAR and SREBP expression
por: LI, GUO-SHENG, et al.
Publicado: (2016)

Alteration of muscle fiber characteristics and the AMPK-SIRT1-PGC-1α axis in skeletal muscle of growing pigs fed low-protein diets with varying branched-chain amino acid ratios
por: Duan, Yehui, et al.
Publicado: (2017)

Celastrol attenuates oxidative stress in the skeletal muscle of diabetic rats by regulating the AMPK-PGC1α-SIRT3 signaling pathway
por: GUAN, YUE, et al.
Publicado: (2016)

GPR40 agonist ameliorates liver X receptor-induced lipid accumulation in liver by activating AMPK pathway
por: Li, Meng, et al.
Publicado: (2016)

Resveratrol Improves the Energy Sensing and Glycolipid Metabolism of Blunt Snout Bream Megalobrama amblycephala Fed High-Carbohydrate Diets by Activating the AMPK–SIRT1–PGC-1α Network
por: Shi, Hua-Juan, et al.
Publicado: (2018)

Periplaneta americana extract ameliorates lipopolysaccharide-induced liver injury by improving mitochondrial dysfunction via the AMPK/PGC-1α signaling pathway
por: Shi, Wei, et al.
Publicado: (2021)

PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascades
por: Liu, Dong, et al.
Publicado: (2019)

Myonectin protects against skeletal muscle dysfunction in male mice through activation of AMPK/PGC1α pathway
por: Ozaki, Yuta, et al.
Publicado: (2023)

Lactobacillus rhamnosus GG Colonization in Early Life Ameliorates Inflammaging of Offspring by Activating SIRT1/AMPK/PGC-1α Pathway
por: Liu, Tianyu, et al.
Publicado: (2021)

Induction of glucose uptake in skeletal muscle by central leptin is mediated by muscle β(2)-adrenergic receptor but not by AMPK
por: Shiuchi, Tetsuya, et al.
Publicado: (2017)

Icariside II, a Naturally Occurring SIRT3 Agonist, Protects against Myocardial Infarction through the AMPK/PGC-1α/Apoptosis Signaling Pathway
por: Li, Yeli, et al.
Publicado: (2022)

Melatonin ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic rats by preserving mitochondrial function: role of AMPK-PGC-1α-SIRT3 signaling
por: Yu, Liming, et al.
Publicado: (2017)

D-allulose ameliorates adiposity through the AMPK-SIRT1-PGC-1α pathway in HFD-induced SD rats
por: Lee, Geum-Hwa, et al.
Publicado: (2021)

Abdominal Massage Alleviates Skeletal Muscle Insulin Resistance by Regulating the AMPK/SIRT1/PGC-1α Signaling Pathway
por: Han, Yiran, et al.
Publicado: (2021)

Studies on the effects of hypothermia combined with hypoxia on rat skeletal muscle and lipid metabolism based on AMPK/PGC1α pathway
por: Ruixia, Zhang, et al.
Publicado: (2021)

Adrenergic modulation of AMPK-dependent autophagy by chronic stress enhances cell proliferation and survival in gastric cancer
por: Zhi, Xiaofei, et al.
Publicado: (2019)

β2-adrenergic receptor agonist counteracts skeletal muscle atrophy and oxidative stress in uremic mice
por: Higashihara, Takaaki, et al.
Publicado: (2021)

Role of PGC-1α signaling in skeletal muscle health and disease
por: Kang, Chounghun, et al.
Publicado: (2012)

AMPK Activation by Metformin Suppresses Abnormal Extracellular Matrix Remodeling in Adipose Tissue and Ameliorates Insulin Resistance in Obesity
por: Luo, Ting, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_s7ub93attq61te3pli0f08vdk4