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Abnormalities in the Von Willebrand-Angiopoietin Axis Contribute to Dysregulated Angiogenesis and Angiodysplasia in Children With a Glenn Circulation

Children with a bidirectional superior cavopulmonary (Glenn) circulation develop angiodysplasia and pulmonary arteriovenous malformations (AVMs). The von Willebrand factor (vWF)–angiopoietin axis plays a major role in AVM formation in multiple diseases. We observed derangements in global angiogenic...

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Detalles Bibliográficos
Autores principales: Bartoli, Carlo R., Hennessy-Strahs, Samson, Dowling, Robert D., Gaynor, J. William, Glatz, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987544/
https://www.ncbi.nlm.nih.gov/pubmed/33778210
http://dx.doi.org/10.1016/j.jacbts.2020.12.014