Inhibition of HECT E3 ligases as potential therapy for COVID-19

SARS-CoV-2 is responsible for the ongoing world-wide pandemic which has already taken more than two million lives. Effective treatments are urgently needed. The enzymatic activity of the HECT-E3 ligase family members has been implicated in the cell egression phase of deadly RNA viruses such as Ebola...

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Detalles Bibliográficos
Autores principales: Novelli, Giuseppe, Liu, Jing, Biancolella, Michela, Alonzi, Tonino, Novelli, Antonio, Patten, J. J., Cocciadiferro, Dario, Agolini, Emanuele, Colona, Vito Luigi, Rizzacasa, Barbara, Giannini, Rosalinda, Bigio, Benedetta, Goletti, Delia, Capobianchi, Maria Rosaria, Grelli, Sandro, Mann, Justin, McKee, Trevor D., Cheng, Ke, Amanat, Fatima, Krammer, Florian, Guarracino, Andrea, Pepe, Gerardo, Tomino, Carlo, Tandjaoui-Lambiotte, Yacine, Uzunhan, Yurdagul, Tubiana, Sarah, Ghosn, Jade, Notarangelo, Luigi D., Su, Helen C., Abel, Laurent, Cobat, Aurélie, Elhanan, Gai, Grzymski, Joseph J., Latini, Andrea, Sidhu, Sachdev S., Jain, Suresh, Davey, Robert A., Casanova, Jean-Laurent, Wei, Wenyi, Pandolfi, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987752/
https://www.ncbi.nlm.nih.gov/pubmed/33762578
http://dx.doi.org/10.1038/s41419-021-03513-1

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