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QSAR Modeling for Multi-Target Drug Discovery: Designing Simultaneous Inhibitors of Proteins in Diverse Pathogenic Parasites

Parasitic diseases remain as unresolved health issues worldwide. While for some parasites the treatments involve drug combinations with serious side effects, for others, chemical therapies are inefficient due to the emergence of drug resistance. This urges the search for novel antiparasitic agents a...

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Detalles Bibliográficos
Autores principales: Kleandrova, Valeria V., Scotti, Luciana, Bezerra Mendonça Junior, Francisco Jaime, Muratov, Eugene, Scotti, Marcus T., Speck-Planche, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987820/
https://www.ncbi.nlm.nih.gov/pubmed/33777898
http://dx.doi.org/10.3389/fchem.2021.634663