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A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets

Type 1 and 2 diabetes (T1/2D) are complex metabolic diseases caused by absolute or relative loss of functional β-cell mass, respectively. Both diseases are influenced by multiple genetic loci that alter disease risk. For many of the disease-associated loci, the causal candidate genes remain to be id...

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Detalles Bibliográficos
Autores principales:	Kaur, Simranjeet, Mirza, Aashiq H., Overgaard, Anne J., Pociot, Flemming, Størling, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987941/ https://www.ncbi.nlm.nih.gov/pubmed/33777101 http://dx.doi.org/10.3389/fgene.2021.630109

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