Cargando…

Deciphering the Prognostic Implications of the Components and Signatures in the Immune Microenvironment of Pancreatic Ductal Adenocarcinoma

Background: The treatment modalities for pancreatic ductal adenocarcinoma (PDAC) are limited and unsatisfactory. Although many novel drugs targeting the tumor microenvironment, such as immune checkpoint inhibitors, have shown promising efficacy for some tumors, few of them significantly prolong the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Rong, Liu, Xiaomeng, Liang, Chen, Hua, Jie, Xu, Jin, Wang, Wei, Meng, Qingcai, Liu, Jiang, Zhang, Bo, Yu, Xianjun, Shi, Si
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987951/ https://www.ncbi.nlm.nih.gov/pubmed/33777046 http://dx.doi.org/10.3389/fimmu.2021.648917

Ejemplares similares

Role of tumor mutation burden-related signatures in the prognosis and immune microenvironment of pancreatic ductal adenocarcinoma
por: Tang, Rong, et al.
Publicado: (2021)

The reciprocal regulation between host tissue and immune cells in pancreatic ductal adenocarcinoma: new insights and therapeutic implications
por: Liu, Xiaomeng, et al.
Publicado: (2019)

Development and Verification of the Hypoxia- and Immune-Associated Prognostic Signature for Pancreatic Ductal Adenocarcinoma
por: Chen, Dongjie, et al.
Publicado: (2021)

From the Immune Profile to the Immunoscore: Signatures for Improving Postsurgical Prognostic Prediction of Pancreatic Neuroendocrine Tumors
por: Wei, Miaoyan, et al.
Publicado: (2021)

Identification of the Roles of a Stemness Index Based on mRNA Expression in the Prognosis and Metabolic Reprograming of Pancreatic Ductal Adenocarcinoma
por: Tang, Rong, et al.
Publicado: (2021)

A PD-L2-based immune marker signature helps to predict survival in resected pancreatic ductal adenocarcinoma
por: Zhang, Yiyin, et al.
Publicado: (2019)

Deciphering the Crosstalk Between Myeloid-Derived Suppressor Cells and Regulatory T Cells in Pancreatic Ductal Adenocarcinoma
por: Siret, Carole, et al.
Publicado: (2020)

Neural Component of the Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma
por: Gola, Michał, et al.
Publicado: (2022)

Tumor microenvironment in pancreatic ductal adenocarcinoma: Implications in immunotherapy
por: Smith, Caitlyn, et al.
Publicado: (2022)

Hyperdense Pancreatic Ductal Adenocarcinoma: Clinical Characteristics and Proteomic Landscape
por: Xu, He, et al.
Publicado: (2021)

Deciphering CHFR Role in Pancreatic Ductal Adenocarcinoma
por: González-Borja, Iranzu, et al.
Publicado: (2021)

The Impact of Immune Microenvironment on the Prognosis of Pancreatic Ductal Adenocarcinoma Based on Multi-Omics Analysis
por: Yang, Bing, et al.
Publicado: (2021)

The role of m6A-related genes in the prognosis and immune microenvironment of pancreatic adenocarcinoma
por: Tang, Rong, et al.
Publicado: (2020)

Identification and Validation of Immune Molecular Subtypes in Pancreatic Ductal Adenocarcinoma: Implications for Prognosis and Immunotherapy
por: Li, Ruiyu, et al.
Publicado: (2021)

Characterization of intratumoral tertiary lymphoid structures in pancreatic ductal adenocarcinoma: cellular properties and prognostic significance
por: Zou, Xuan, et al.
Publicado: (2023)

Prognostic value of biomarkers in the tumor microenvironment of pancreatic ductal adenocarcinoma
por: Mishra, Nitish K., et al.
Publicado: (2020)

Pancreatic Ductal Adenocarcinoma: A Strong Imbalance of Good and Bad Immunological Cops in the Tumor Microenvironment
por: Foucher, Etienne D., et al.
Publicado: (2018)

Quantitative Spatial Profiling of Immune Populations in Pancreatic Ductal Adenocarcinoma Reveals Tumor Microenvironment Heterogeneity and Prognostic Biomarkers
por: Mi, Haoyang, et al.
Publicado: (2022)

Single-cell profiling of microenvironment components by spatial localization in pancreatic ductal adenocarcinoma
por: Han, Song, et al.
Publicado: (2022)

Comprehensive Analysis of Expression, Prognostic Value, and Immune Infiltration for Ubiquitination-Related FBXOs in Pancreatic Ductal Adenocarcinoma
por: Zhang, Yalu, et al.
Publicado: (2022)

Metastatic phenotype and immunosuppressive tumour microenvironment in pancreatic ductal adenocarcinoma: Key role of the urokinase plasminogen activator (PLAU)
por: Hosen, S. M. Zahid, et al.
Publicado: (2022)

Single-cell sequencing reveals heterogeneity between pancreatic adenosquamous carcinoma and pancreatic ductal adenocarcinoma with prognostic value
por: Zhang, Deyu, et al.
Publicado: (2022)

The Role of PDGFRA in Predicting Oncological and Immune Characteristics in Pancreatic Ductal Adenocarcinoma
por: Wu, Zijian, et al.
Publicado: (2022)

Intra-tumoral infiltration of adipocyte facilitates the activation of antitumor immune response in pancreatic ductal adenocarcinoma
por: Liu, Xiaomeng, et al.
Publicado: (2022)

Targeting Pancreatic Ductal Adenocarcinoma Acidic Microenvironment
por: Cruz-Monserrate, Zobeida, et al.
Publicado: (2014)

Prognostic Fifteen-Gene Signature for Early Stage Pancreatic Ductal Adenocarcinoma
por: Chen, Dung-Tsa, et al.
Publicado: (2015)

Establishing and validating an ADCP-related prognostic signature in pancreatic ductal adenocarcinoma
por: Zhang, Deyu, et al.
Publicado: (2022)

Novel prognostic gene signature for pancreatic ductal adenocarcinoma based on hypoxia
por: Ren, Min, et al.
Publicado: (2023)

Mechanisms Governing Immunotherapy Resistance in Pancreatic Ductal Adenocarcinoma
por: Schmiechen, Zoe C., et al.
Publicado: (2021)

Immune features of the peritumoral stroma in pancreatic ductal adenocarcinoma
por: Ahmed, Azaz, et al.
Publicado: (2022)

Prognostic Stratification Based on HIF-1 Signaling for Evaluating Hypoxic Status and Immune Infiltration in Pancreatic Ductal Adenocarcinomas
por: Zhuang, Hongkai, et al.
Publicado: (2021)

Pancreatic ductal adenocarcinoma immune microenvironment and immunotherapy prospects
por: Li, Ke-Yu, et al.
Publicado: (2020)

Prognostic value of immune factors in the tumor microenvironment of patients with pancreatic ductal adenocarcinoma
por: Kiryu, Sachie, et al.
Publicado: (2021)

Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis
por: Rong, Zeyin, et al.
Publicado: (2021)

A novel genomic instability-derived lncRNA signature to predict prognosis and immune characteristics of pancreatic ductal adenocarcinoma
por: Yang, Huijie, et al.
Publicado: (2022)

Identifying a baicalein-related prognostic signature contributes to prognosis prediction and tumor microenvironment of pancreatic cancer
por: Zhang, Citing, et al.
Publicado: (2023)

The value of a metabolic reprogramming-related gene signature for pancreatic adenocarcinoma prognosis prediction
por: Tan, Zhen, et al.
Publicado: (2020)

Integrated analysis revealed hypoxia signatures and LDHA related to tumor cell dedifferentiation and unfavorable prognosis in pancreatic adenocarcinoma: Hypoxia in PDAC
por: Dong, Mingwei, et al.
Publicado: (2023)

Prognostic Risk Model and Tumor Immune Environment Modulation of m5C-Related LncRNAs in Pancreatic Ductal Adenocarcinoma
por: Yuan, Hao, et al.
Publicado: (2021)

Prognostic biomarkers related to tumoral microenvironment in pancreatic ductal adenocarcinoma: a systematic review
por: Constantin, Alina Liliana, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_45ibnjq8oicp6prknrqeqrd4i4