Astaxanthin protects against early acute kidney injury in severely burned rats by inactivating the TLR4/MyD88/NF-κB axis and upregulating heme oxygenase-1

Early acute kidney injury (AKI) contributes to severe morbidity and mortality in critically burned patients. Renal inflammation plays a vital role in the progression of early AKI, acting as a therapeutic target. Astaxanthin (ATX) is a strong antioxidant widely distributed in marine organisms that ex...

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Detalles Bibliográficos
Autores principales: Guo, Songxue, Guo, Linsen, Fang, Quan, Yu, Meirong, Zhang, Liping, You, Chuangang, Wang, Xingang, Liu, Yong, Han, Chunmao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988001/
https://www.ncbi.nlm.nih.gov/pubmed/33758309
http://dx.doi.org/10.1038/s41598-021-86146-w

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