Cargando…

Structure based analysis of K(ATP) channel with a DEND syndrome mutation in murine skeletal muscle

Developmental delay, epilepsy, and neonatal diabetes (DEND) syndrome, the most severe end of neonatal diabetes mellitus, is caused by mutation in the ATP-sensitive potassium (K(ATP)) channel. In addition to diabetes, DEND patients present muscle weakness as one of the symptoms, and although the musc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Horita, Shoichiro, Ono, Tomoyuki, Gonzalez-Resines, Saul, Ono, Yuko, Yamachi, Megumi, Zhao, Songji, Domene, Carmen, Maejima, Yuko, Shimomura, Kenju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988048/ https://www.ncbi.nlm.nih.gov/pubmed/33758250 http://dx.doi.org/10.1038/s41598-021-86121-5

Ejemplares similares

K(ATP) Channel Mutations and Neonatal Diabetes
por: Shimomura, Kenju, et al.
Publicado: (2017)

Goshajinkigan, a Traditional Japanese Medicine, Suppresses Voltage-Gated Sodium Channel Nav1.4 Currents in C2C12 Cells
por: Imai, Ryota, et al.
Publicado: (2020)

Memantine has no effect on K(ATP) channels in pancreatic β cells
por: Imai, Ryota, et al.
Publicado: (2018)

TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice
por: Ono, Yuko, et al.
Publicado: (2020)

Dose Dependent Effect of Sulfamethoxazole on Inhibiting K(ATP) Channel of Mouse Pancreatic β Cell
por: Ogata, Hiroshi, et al.
Publicado: (2023)

The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats
por: Maejima, Yuko, et al.
Publicado: (2019)

Early life high-fat diet exposure evokes normal weight obesity
por: Maejima, Yuko, et al.
Publicado: (2020)

Soluble interleukin-2 receptor as a predictive and prognostic marker for patients with familial breast cancer
por: Gonda, Kenji, et al.
Publicado: (2021)

Identification of oxytocin receptor activating chemical components from traditional Japanese medicines
por: Maejima, Yuko, et al.
Publicado: (2021)

Association between cognitive impairment patient with solid cancer and insulin resistance
por: Gonda, Kenji, et al.
Publicado: (2019)

Effect of fenofibrate and selective PPARα modulator (SPPARMα), pemafibrate on KATP channel activity and insulin secretion
por: Kitamura, Shigeki, et al.
Publicado: (2023)

The hypothalamus to brainstem circuit suppresses late-onset body weight gain
por: Maejima, Yuko, et al.
Publicado: (2019)

The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity
por: Maejima, Yuko, et al.
Publicado: (2021)

C188-9, a specific inhibitor of STAT3 signaling, prevents thermal burn-induced skeletal muscle wasting in mice
por: Ono, Yuko, et al.
Publicado: (2022)

A Potential Route of Capsaicin to Its Binding Site in the TRPV1 Ion Channel
por: Domene, Carmen, et al.
Publicado: (2022)

Efficacy of SGLT2 inhibitors as additional treatment in Japanese type 2 diabetic patients: second or third choice?
por: Fujiwara, Makoto, et al.
Publicado: (2022)

Cognitive deficits and impaired hippocampal long-term potentiation in K(ATP)-induced DEND syndrome
por: Yahil, Shaul, et al.
Publicado: (2021)

MLH1 germline mutation associated with Lynch syndrome in a family followed for more than 45 years
por: Momma, Tomoyuki, et al.
Publicado: (2019)

The effect of avertin anesthesia and a mixture of three types of anesthetic agents on food intakeand body weight in high fat-induced obese maleand female mice
por: Maejima, Yuko, et al.
Publicado: (2018)

Evaluation of organ glucose metabolism by (18)F-FDG accumulation with insulin loading in aged mice compared with young normal mice
por: Zhao, Jingmin, et al.
Publicado: (2021)

Evaluation of Effect of Ninjin'yoeito on Regional Brain Glucose Metabolism by (18)F-FDG Autoradiography With Insulin Loading in Aged Mice
por: Zhao, Jingmin, et al.
Publicado: (2021)

The effects of ninjin’yoeito on the electrophysiological properties of dopamine neurons in the ventral tegmental area/substantia nigra pars compacta and medium spiny neurons in the nucleus accumbens
por: Imai, Ryota, et al.
Publicado: (2022)

Impact of Green Tea Catechin Ingestion on the Pharmacokinetics of Lisinopril in Healthy Volunteers
por: Misaka, Shingen, et al.
Publicado: (2020)

Exposure of Fexofenadine, but Not Pseudoephedrine, Is Markedly Decreased by Green Tea Extract in Healthy Volunteers
por: Misaka, Shingen, et al.
Publicado: (2022)

Non-alcoholic Fatty Liver Disease Is a Risk Factor for Type 2 Diabetes in Middle-aged Japanese Men and Women
por: Tokita, Yoshiharu, et al.
Publicado: (2017)

Defensa da lingua dende o acelerador de partículas
Publicado: (2009)

Detection of NUCB2/nesfatin-1 in cerebrospinal fluid of multiple sclerosis patients
por: Shimizu, Masaru, et al.
Publicado: (2020)

Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple-negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis complex: a case report
por: Gonda, Kenji, et al.
Publicado: (2019)

Poland syndrome accompanied by internal iliac artery supply disruption sequence: a case report
por: Gonda, Kenji, et al.
Publicado: (2018)

DEND Syndrome with Heterozygous KCNJ11 Mutation Successfully Treated with Sulfonylurea
por: Cho, Ja Hyang, et al.
Publicado: (2017)

dendPoint: a web resource for dendrimer pharmacokinetics investigation and prediction
por: Kaminskas, Lisa M., et al.
Publicado: (2019)

Novel Perspectives of Super-High Dose Glybenclamide in an Infant With DEND Syndrome
por: Barash, Galia, et al.
Publicado: (2021)

Metal-Induced Fluorescence Quenching of Photoconvertible Fluorescent Protein DendFP
por: Kim, In Jung, et al.
Publicado: (2022)

Impact of sex, fat distribution and initial body weight on oxytocin’s body weight regulation
por: Maejima, Yuko, et al.
Publicado: (2017)

Hexosamine pathway but not interstitial changes mediates glucotoxicity in pancreatic β-cells as assessed by cytosolic Ca(2+) response to glucose
por: Yanagida, Kazuhiro, et al.
Publicado: (2014)

A universally conserved residue in the SUR1 subunit of the K(ATP) channel is essential for translating nucleotide binding at SUR1 into channel opening
por: de Wet, Heidi, et al.
Publicado: (2012)

Development of I(KATP) Ion Channel Blockers Targeting Sulfonylurea Resistant Mutant K(IR)6.2 Based Channels for Treating DEND Syndrome
por: Houtman, Marien J. C., et al.
Publicado: (2022)

Functional Characterization of a Novel KCNJ11 in Frame Mutation-Deletion Associated with Infancy-Onset Diabetes and a Mild Form of Intermediate DEND: A Battle between K(ATP) Gain of Channel Activity and Loss of Channel Expression
por: Lin, Yu-Wen, et al.
Publicado: (2013)

Severe Developmental Delay, Epilepsy and Neonatal Diabetes (DEND) Syndrome: A Case Report*
por: Helmi, Muhd Alwi Muhd, et al.
Publicado: (2020)

The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expression in Hepatocellular Carcinoma
por: Jojima, Teruo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_efpql2n0scb2mnsbbes5rs43fp