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Prenatally traumatized mice reveal hippocampal methylation and expression changes of the stress-related genes Crhr1 and Fkbp5

In our previous study, we found that prenatal trauma exposure leads to an anxiety phenotype in mouse pups, characterized by increased corticosterone levels and increased anxiety-like behavior. In order to understand the mechanisms by which aversive in utero experience leads to these long-lasting beh...

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Detalles Bibliográficos
Autores principales: Plank, Anne-Christine, Frey, Stefan, Basedow, Lukas Andreas, Solati, Jalal, Canneva, Fabio, von Hörsten, Stephan, Kratz, Oliver, Moll, Gunther H., Golub, Yulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988147/
https://www.ncbi.nlm.nih.gov/pubmed/33758173
http://dx.doi.org/10.1038/s41398-021-01293-y