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Wnt/β-catenin signaling mediates the abnormal osteogenic and adipogenic capabilities of bone marrow mesenchymal stem cells from chronic graft-versus-host disease patients

Chronic graft-versus-host disease (cGVHD) is the main cause of non-relapse mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Mesenchymal stem cells (MSCs) in bone marrow (BM) remain unclear in the pathophysiology of cGVHD. In this study, we analyzed BM-MSCs from 66 pati...

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Detalles Bibliográficos
Autores principales:	Qi, Han-zhou, Ye, Yi-ling, Suo, Yuan, Qu, Hong, Zhang, Hai-yan, Yang, Kai-bo, Fan, Zhi-ping, Huang, Fen, Xuan, Li, Chen, Yan-qiu, Jin, Hua, Liu, Qi-fa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988169/ https://www.ncbi.nlm.nih.gov/pubmed/33758171 http://dx.doi.org/10.1038/s41419-021-03570-6

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