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Impact of vitamin D level on glycemic control in diabetes mellitus type 2 in Duhok
BACKGROUND: Vitamin D deficiency is prevalent in most parts of the world. Its insufficiency or deficiency is implicated in bone diseases, some cancers, infectious diseases, heart disease, autoimmune and metabolic diseases including type 2 diabetes mellitus. RESULTS: The mean age of patients was 49.9...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988274/ https://www.ncbi.nlm.nih.gov/pubmed/33786167 http://dx.doi.org/10.1016/j.amsu.2021.102208 |
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author | Salih, Yosuf Abdullah Rasool, Mohammed T. Ahmed, Idris Haji Mohammed, Ayad Ahmad |
author_facet | Salih, Yosuf Abdullah Rasool, Mohammed T. Ahmed, Idris Haji Mohammed, Ayad Ahmad |
author_sort | Salih, Yosuf Abdullah |
collection | PubMed |
description | BACKGROUND: Vitamin D deficiency is prevalent in most parts of the world. Its insufficiency or deficiency is implicated in bone diseases, some cancers, infectious diseases, heart disease, autoimmune and metabolic diseases including type 2 diabetes mellitus. RESULTS: The mean age of patients was 49.94 ± 9.36, while the mean age the controls was 48.95 ± 10.56. Females constituted 56.1% and males 43.9% in the cases group, while for the control group females were 54.8% and males were 43.9%. Low vitamin D levels were detected in 110 (71%) of cases and 63 (40.6%) of controls. There was a significant difference in vitamin D levels among cases and controls (p < 0.001), vitamin D level was lower among females compared to males, p < 0.001 and those living in urban areas compared to rural areas, p < 0.001, BMI and dyslipidemia had a significant effect on vitamin D levels among diabetics, p values 0.002 and < 0.001 respectively. The serum 25(OH)-D level was significantly lower in patients with poor glycemic control compared to those with good glycemic control and in patients with a diabetes duration greater than 5 years, p values < 0.001 and 0.002 respectively. No significant correlation was detected with age and smoking, p values 0.181 and 0.260 respectively. CONCLUSION: There is a high prevalence of hypo-vitaminosis D among patients with type-2 diabetes, particularly among patients with poor glycemic control and in those with longer diabetes durations. Vitamin-D deficiency is more prevalence in females, and those living in urban areas, those with obesity and patients with dyslipidemia. |
format | Online Article Text |
id | pubmed-7988274 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-79882742021-03-29 Impact of vitamin D level on glycemic control in diabetes mellitus type 2 in Duhok Salih, Yosuf Abdullah Rasool, Mohammed T. Ahmed, Idris Haji Mohammed, Ayad Ahmad Ann Med Surg (Lond) Case-controlled Study BACKGROUND: Vitamin D deficiency is prevalent in most parts of the world. Its insufficiency or deficiency is implicated in bone diseases, some cancers, infectious diseases, heart disease, autoimmune and metabolic diseases including type 2 diabetes mellitus. RESULTS: The mean age of patients was 49.94 ± 9.36, while the mean age the controls was 48.95 ± 10.56. Females constituted 56.1% and males 43.9% in the cases group, while for the control group females were 54.8% and males were 43.9%. Low vitamin D levels were detected in 110 (71%) of cases and 63 (40.6%) of controls. There was a significant difference in vitamin D levels among cases and controls (p < 0.001), vitamin D level was lower among females compared to males, p < 0.001 and those living in urban areas compared to rural areas, p < 0.001, BMI and dyslipidemia had a significant effect on vitamin D levels among diabetics, p values 0.002 and < 0.001 respectively. The serum 25(OH)-D level was significantly lower in patients with poor glycemic control compared to those with good glycemic control and in patients with a diabetes duration greater than 5 years, p values < 0.001 and 0.002 respectively. No significant correlation was detected with age and smoking, p values 0.181 and 0.260 respectively. CONCLUSION: There is a high prevalence of hypo-vitaminosis D among patients with type-2 diabetes, particularly among patients with poor glycemic control and in those with longer diabetes durations. Vitamin-D deficiency is more prevalence in females, and those living in urban areas, those with obesity and patients with dyslipidemia. Elsevier 2021-03-05 /pmc/articles/PMC7988274/ /pubmed/33786167 http://dx.doi.org/10.1016/j.amsu.2021.102208 Text en © 2021 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case-controlled Study Salih, Yosuf Abdullah Rasool, Mohammed T. Ahmed, Idris Haji Mohammed, Ayad Ahmad Impact of vitamin D level on glycemic control in diabetes mellitus type 2 in Duhok |
title | Impact of vitamin D level on glycemic control in diabetes mellitus type 2 in Duhok |
title_full | Impact of vitamin D level on glycemic control in diabetes mellitus type 2 in Duhok |
title_fullStr | Impact of vitamin D level on glycemic control in diabetes mellitus type 2 in Duhok |
title_full_unstemmed | Impact of vitamin D level on glycemic control in diabetes mellitus type 2 in Duhok |
title_short | Impact of vitamin D level on glycemic control in diabetes mellitus type 2 in Duhok |
title_sort | impact of vitamin d level on glycemic control in diabetes mellitus type 2 in duhok |
topic | Case-controlled Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988274/ https://www.ncbi.nlm.nih.gov/pubmed/33786167 http://dx.doi.org/10.1016/j.amsu.2021.102208 |
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