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Maternal Diabetes Impairs Insulin and IGF-1 Receptor Expression and Signaling in Human Placenta

BACKGROUND: Maternal high blood glucose during pregnancy increases the risk for both maternal and fetal adverse outcomes. The mechanisms underlying the regulator effects of hyperglycemia on placental development and growth have not been fully illustrated yet. The placenta expresses high amounts of b...

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Detalles Bibliográficos
Autores principales: Tumminia, Andrea, Scalisi, Nunzio M., Milluzzo, Agostino, Ettore, Giuseppe, Vigneri, Riccardo, Sciacca, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988311/
https://www.ncbi.nlm.nih.gov/pubmed/33776919
http://dx.doi.org/10.3389/fendo.2021.621680

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