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USP22 promotes melanoma and BRAF inhibitor resistance via YAP stabilization

Yes-associated protein (YAP) is a conserved transcriptional coactivator that plays key roles in controlling organ size, tumorigenesis and drug resistance. Emerging evidence shows that YAP is overexpressed and associated with resistance to BRAF inhibitor treatment in melanoma. However, the mechanism...

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Detalles Bibliográficos
Autores principales:	Wei, Ying, Jiang, Ziyun, Lu, Jianfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988733/ https://www.ncbi.nlm.nih.gov/pubmed/33777217 http://dx.doi.org/10.3892/ol.2021.12655

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