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Exosomes from human umbilical cord mesenchymal stem cells attenuate the inflammation of severe steroid-resistant asthma by reshaping macrophage polarization

BACKGROUND: Severe, steroid-resistant asthma (SSRA) is a serious clinical problem in asthma management. Affected patients have severe clinical symptoms, worsened quality of life, and do not respond to steroid, a mainstay steroid treatment of asthma. Thus, effective therapies are urgently needed. Exo...

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Detalles Bibliográficos
Autores principales: Dong, Bing, Wang, Chao, Zhang, Jing, Zhang, Jinrong, Gu, Yinuo, Guo, Xiaoping, Zuo, Xu, Pan, He, Hsu, Alan Chen-Yu, Wang, Guoqiang, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988945/
https://www.ncbi.nlm.nih.gov/pubmed/33761997
http://dx.doi.org/10.1186/s13287-021-02244-6