Revascularization of acute stent thrombosis after carotid artery stenting in a CYP2C19*2 heterozygote patient

Carotid artery stenting (CAS) is an alternative strategy to carotid endarterectomy for the prevention of ischemic stroke. Acute carotid stent thrombosis (ACST) is an extremely rare but devastating complication of CAS. Although cases of successful recanalization have been reported, there is still a l...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Wang, Yan, Wang, Pian, Li, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989125/
https://www.ncbi.nlm.nih.gov/pubmed/33745326
http://dx.doi.org/10.1177/03000605211001191
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author Wei, Wei
Wang, Yan
Wang, Pian
Li, Zheng
author_facet Wei, Wei
Wang, Yan
Wang, Pian
Li, Zheng
author_sort Wei, Wei
collection PubMed
description Carotid artery stenting (CAS) is an alternative strategy to carotid endarterectomy for the prevention of ischemic stroke. Acute carotid stent thrombosis (ACST) is an extremely rare but devastating complication of CAS. Although cases of successful recanalization have been reported, there is still a lack of experience regarding the choice of ACST treatment methods and the timing of such treatments, especially when patients are confirmed CYP2C19*2 heterozygotes. Here, we report a case of successful revascularization after ACST in a patient with CYP2C19*2 heterozygosity. We also review the literature and discuss appropriate treatment strategies for this devastating and rare event.
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spelling pubmed-79891252021-04-02 Revascularization of acute stent thrombosis after carotid artery stenting in a CYP2C19*2 heterozygote patient Wei, Wei Wang, Yan Wang, Pian Li, Zheng J Int Med Res Case Reports Carotid artery stenting (CAS) is an alternative strategy to carotid endarterectomy for the prevention of ischemic stroke. Acute carotid stent thrombosis (ACST) is an extremely rare but devastating complication of CAS. Although cases of successful recanalization have been reported, there is still a lack of experience regarding the choice of ACST treatment methods and the timing of such treatments, especially when patients are confirmed CYP2C19*2 heterozygotes. Here, we report a case of successful revascularization after ACST in a patient with CYP2C19*2 heterozygosity. We also review the literature and discuss appropriate treatment strategies for this devastating and rare event. SAGE Publications 2021-03-21 /pmc/articles/PMC7989125/ /pubmed/33745326 http://dx.doi.org/10.1177/03000605211001191 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Reports
Wei, Wei
Wang, Yan
Wang, Pian
Li, Zheng
Revascularization of acute stent thrombosis after carotid artery stenting in a CYP2C19*2 heterozygote patient
title Revascularization of acute stent thrombosis after carotid artery stenting in a CYP2C19*2 heterozygote patient
title_full Revascularization of acute stent thrombosis after carotid artery stenting in a CYP2C19*2 heterozygote patient
title_fullStr Revascularization of acute stent thrombosis after carotid artery stenting in a CYP2C19*2 heterozygote patient
title_full_unstemmed Revascularization of acute stent thrombosis after carotid artery stenting in a CYP2C19*2 heterozygote patient
title_short Revascularization of acute stent thrombosis after carotid artery stenting in a CYP2C19*2 heterozygote patient
title_sort revascularization of acute stent thrombosis after carotid artery stenting in a cyp2c19*2 heterozygote patient
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989125/
https://www.ncbi.nlm.nih.gov/pubmed/33745326
http://dx.doi.org/10.1177/03000605211001191
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AT wangpian revascularizationofacutestentthrombosisaftercarotidarterystentinginacyp2c192heterozygotepatient
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