A Case of Severe Acute Respiratory Syndrome Coronavirus 2 Treatment With Remdesivir in a Hepatitis C-Coinfected Patient Resulting in Temporary Viral Control and Posttreatment Flare

We report a case of a man with chronic hepatitis C infection treated with remdesivir for COVID-19, resulting in lowered HCV viral load, followed by a rebound after its discontinuation. Concomitant treatment with tocilizumab possibly caused loss of anti-HBs.

Detalles Bibliográficos
Autores principales: da Cunha, Maria Ribeiro, Rodrigues, Inês Coelho, Trigueiros, Frederico, Freitas, Luís Carlos, Braz, Sandra, Cota Medeiros, Fábio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989155/
https://www.ncbi.nlm.nih.gov/pubmed/33880393
http://dx.doi.org/10.1093/ofid/ofab100
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author da Cunha, Maria Ribeiro
Rodrigues, Inês Coelho
Trigueiros, Frederico
Freitas, Luís Carlos
Braz, Sandra
Cota Medeiros, Fábio
author_facet da Cunha, Maria Ribeiro
Rodrigues, Inês Coelho
Trigueiros, Frederico
Freitas, Luís Carlos
Braz, Sandra
Cota Medeiros, Fábio
author_sort da Cunha, Maria Ribeiro
collection PubMed
description We report a case of a man with chronic hepatitis C infection treated with remdesivir for COVID-19, resulting in lowered HCV viral load, followed by a rebound after its discontinuation. Concomitant treatment with tocilizumab possibly caused loss of anti-HBs.
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spelling pubmed-79891552021-04-01 A Case of Severe Acute Respiratory Syndrome Coronavirus 2 Treatment With Remdesivir in a Hepatitis C-Coinfected Patient Resulting in Temporary Viral Control and Posttreatment Flare da Cunha, Maria Ribeiro Rodrigues, Inês Coelho Trigueiros, Frederico Freitas, Luís Carlos Braz, Sandra Cota Medeiros, Fábio Open Forum Infect Dis Brief Reports We report a case of a man with chronic hepatitis C infection treated with remdesivir for COVID-19, resulting in lowered HCV viral load, followed by a rebound after its discontinuation. Concomitant treatment with tocilizumab possibly caused loss of anti-HBs. Oxford University Press 2021-03-02 /pmc/articles/PMC7989155/ /pubmed/33880393 http://dx.doi.org/10.1093/ofid/ofab100 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
da Cunha, Maria Ribeiro
Rodrigues, Inês Coelho
Trigueiros, Frederico
Freitas, Luís Carlos
Braz, Sandra
Cota Medeiros, Fábio
A Case of Severe Acute Respiratory Syndrome Coronavirus 2 Treatment With Remdesivir in a Hepatitis C-Coinfected Patient Resulting in Temporary Viral Control and Posttreatment Flare
title A Case of Severe Acute Respiratory Syndrome Coronavirus 2 Treatment With Remdesivir in a Hepatitis C-Coinfected Patient Resulting in Temporary Viral Control and Posttreatment Flare
title_full A Case of Severe Acute Respiratory Syndrome Coronavirus 2 Treatment With Remdesivir in a Hepatitis C-Coinfected Patient Resulting in Temporary Viral Control and Posttreatment Flare
title_fullStr A Case of Severe Acute Respiratory Syndrome Coronavirus 2 Treatment With Remdesivir in a Hepatitis C-Coinfected Patient Resulting in Temporary Viral Control and Posttreatment Flare
title_full_unstemmed A Case of Severe Acute Respiratory Syndrome Coronavirus 2 Treatment With Remdesivir in a Hepatitis C-Coinfected Patient Resulting in Temporary Viral Control and Posttreatment Flare
title_short A Case of Severe Acute Respiratory Syndrome Coronavirus 2 Treatment With Remdesivir in a Hepatitis C-Coinfected Patient Resulting in Temporary Viral Control and Posttreatment Flare
title_sort case of severe acute respiratory syndrome coronavirus 2 treatment with remdesivir in a hepatitis c-coinfected patient resulting in temporary viral control and posttreatment flare
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989155/
https://www.ncbi.nlm.nih.gov/pubmed/33880393
http://dx.doi.org/10.1093/ofid/ofab100
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