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Caffeine modulates pharmacokinetic and pharmacodynamic profiles of pioglitazone in diabetic rats: Impact on therapeutics

OBJECTIVES: To determine the influence of caffeine on pharmacokinetics and pharmacodynamics of pioglitazone (PIO) in diabetic rats. METHODS: This was a preclinical study conducted in the College of Pharmacy, Najran University, Saudi Arabia, using 5 groups of Wistar rats: normal rats, untreated diabe...

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Detalles Bibliográficos
Autores principales:	Alshabi, Ali M., Alkahtani, Saad A., Shaikh, Ibrahim A., Habeeb, Mohammed S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Saudi Medical Journal 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989285/ https://www.ncbi.nlm.nih.gov/pubmed/33563733 http://dx.doi.org/10.15537/smj.2021.2.25695

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