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COVID-19, an Incentive to Tackle Sugar in Hospitals and at Home

Obesity and metabolic disease are thwarting our efforts to recover from COVID-19. Chronic inflammation is a key feature of both COVID-19 and the metabolic syndrome. Sugar consumption in particular has been shown to affect COVID-19 mortality by contributing to the chronic inflammatory state. Restrict...

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Autor principal: Vazirani, Anuraag A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989335/
https://www.ncbi.nlm.nih.gov/pubmed/33977196
http://dx.doi.org/10.1210/jendso/bvab037
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author Vazirani, Anuraag A
author_facet Vazirani, Anuraag A
author_sort Vazirani, Anuraag A
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description Obesity and metabolic disease are thwarting our efforts to recover from COVID-19. Chronic inflammation is a key feature of both COVID-19 and the metabolic syndrome. Sugar consumption in particular has been shown to affect COVID-19 mortality by contributing to the chronic inflammatory state. Restriction of free sugar intake has a measurable effect on disease-predicting physiological parameters in as little as 9 days. The rapid reduction in inflammation following fructose restriction is key in the context of the COVID-19 pandemic, as COVID-19 exacerbates the same inflammatory pathways as those driven by the metabolic syndrome. Healthcare providers have a duty to implement international recommendations of reduced free sugar intake. By doing so, they could reduce the chronic inflammatory burden contributing to COVID-19 patients’ demise. Further, it would set a precedent for reducing the risk of severe disease in the uninfected, by maximizing their potential metabolic health in the context of an infection predicated on its disruption.
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spelling pubmed-79893352021-04-01 COVID-19, an Incentive to Tackle Sugar in Hospitals and at Home Vazirani, Anuraag A J Endocr Soc Perspective Obesity and metabolic disease are thwarting our efforts to recover from COVID-19. Chronic inflammation is a key feature of both COVID-19 and the metabolic syndrome. Sugar consumption in particular has been shown to affect COVID-19 mortality by contributing to the chronic inflammatory state. Restriction of free sugar intake has a measurable effect on disease-predicting physiological parameters in as little as 9 days. The rapid reduction in inflammation following fructose restriction is key in the context of the COVID-19 pandemic, as COVID-19 exacerbates the same inflammatory pathways as those driven by the metabolic syndrome. Healthcare providers have a duty to implement international recommendations of reduced free sugar intake. By doing so, they could reduce the chronic inflammatory burden contributing to COVID-19 patients’ demise. Further, it would set a precedent for reducing the risk of severe disease in the uninfected, by maximizing their potential metabolic health in the context of an infection predicated on its disruption. Oxford University Press 2021-03-06 /pmc/articles/PMC7989335/ /pubmed/33977196 http://dx.doi.org/10.1210/jendso/bvab037 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Perspective
Vazirani, Anuraag A
COVID-19, an Incentive to Tackle Sugar in Hospitals and at Home
title COVID-19, an Incentive to Tackle Sugar in Hospitals and at Home
title_full COVID-19, an Incentive to Tackle Sugar in Hospitals and at Home
title_fullStr COVID-19, an Incentive to Tackle Sugar in Hospitals and at Home
title_full_unstemmed COVID-19, an Incentive to Tackle Sugar in Hospitals and at Home
title_short COVID-19, an Incentive to Tackle Sugar in Hospitals and at Home
title_sort covid-19, an incentive to tackle sugar in hospitals and at home
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989335/
https://www.ncbi.nlm.nih.gov/pubmed/33977196
http://dx.doi.org/10.1210/jendso/bvab037
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