The role of miRNAs in COVID-19 disease

Nowadays, the SARS Coronavirus 2 (SARS-CoV-2) infection is recognized as the primary cause of mortality in humans. SARS-CoV-2 is transmitted through human-to-human contact and is asymptomatic in most patients. In addition to approved vaccines against SARS-CoV-2 infection, miRNAs may also be promisin...

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Autores principales: Fani, Mona, Zandi, Milad, Ebrahimi, Saeedeh, Soltani, Saber, Abbasi, Samaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989380/
http://dx.doi.org/10.2217/fvl-2020-0389
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author Fani, Mona
Zandi, Milad
Ebrahimi, Saeedeh
Soltani, Saber
Abbasi, Samaneh
author_facet Fani, Mona
Zandi, Milad
Ebrahimi, Saeedeh
Soltani, Saber
Abbasi, Samaneh
author_sort Fani, Mona
collection PubMed
description Nowadays, the SARS Coronavirus 2 (SARS-CoV-2) infection is recognized as the primary cause of mortality in humans. SARS-CoV-2 is transmitted through human-to-human contact and is asymptomatic in most patients. In addition to approved vaccines against SARS-CoV-2 infection, miRNAs may also be promising options against this new virus. miRNAs are small and noncoding RNAs 18–25 nucleotides in length that target the mRNAs to degrade them or obstruct their translation miRNAs act as an observer in cells. This study reviewed the literature on the potential role of cellular miRNAs in the SARS-CoV-2-host interplay as a therapeutic option in COVID-19 patients.
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spelling pubmed-79893802021-03-24 The role of miRNAs in COVID-19 disease Fani, Mona Zandi, Milad Ebrahimi, Saeedeh Soltani, Saber Abbasi, Samaneh Future Virol Review Nowadays, the SARS Coronavirus 2 (SARS-CoV-2) infection is recognized as the primary cause of mortality in humans. SARS-CoV-2 is transmitted through human-to-human contact and is asymptomatic in most patients. In addition to approved vaccines against SARS-CoV-2 infection, miRNAs may also be promising options against this new virus. miRNAs are small and noncoding RNAs 18–25 nucleotides in length that target the mRNAs to degrade them or obstruct their translation miRNAs act as an observer in cells. This study reviewed the literature on the potential role of cellular miRNAs in the SARS-CoV-2-host interplay as a therapeutic option in COVID-19 patients. Future Medicine Ltd 2021-03-24 2021-03 /pmc/articles/PMC7989380/ http://dx.doi.org/10.2217/fvl-2020-0389 Text en © 2021 Future Medicine Ltd This work is licensed under the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/)
spellingShingle Review
Fani, Mona
Zandi, Milad
Ebrahimi, Saeedeh
Soltani, Saber
Abbasi, Samaneh
The role of miRNAs in COVID-19 disease
title The role of miRNAs in COVID-19 disease
title_full The role of miRNAs in COVID-19 disease
title_fullStr The role of miRNAs in COVID-19 disease
title_full_unstemmed The role of miRNAs in COVID-19 disease
title_short The role of miRNAs in COVID-19 disease
title_sort role of mirnas in covid-19 disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989380/
http://dx.doi.org/10.2217/fvl-2020-0389
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