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Predictive association of ABCB1 C3435T genetic polymorphism with the efficacy or safety of lopinavir and ritonavir in coronavirus disease-2019 patients
Lopinavir and ritonavir are substrates of permeability glycoprotein encoded by ABCB1. The efficacy and safety of these drugs is unknown in coronavirus disease-2019 (COVID-19) patients affected by ABCB1 genetic variability. Patients carrying one or two copies of the ABCB1 C3435T were predictively con...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Future Medicine Ltd
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989382/ https://www.ncbi.nlm.nih.gov/pubmed/33759544 http://dx.doi.org/10.2217/pgs-2020-0096 |