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The Association Between Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Post–COVID-19 Syndrome in Healthcare Workers
It is currently unknown how post-COVID-19 syndrome (PCS) may affect those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This longitudinal study includes healthcare staff who tested positive for SARS-CoV-2 between March and April 2020, with follow-up of their antibody ti...
| Autores principales: | , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989400/ https://www.ncbi.nlm.nih.gov/pubmed/33675366 http://dx.doi.org/10.1093/infdis/jiab120 |
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| author | Pereira, Christopher Harris, Benjamin H L Di Giovannantonio, Matteo Rosadas, Carolina Short, Charlotte-Eve Quinlan, Rachael Sureda-Vives, Macià Fernandez, Natalia Day-Weber, Isaac Khan, Maryam Marchesin, Federica Katsanovskaja, Ksenia Parker, Eleanor Taylor, Graham P Tedder, Richard S McClure, Myra O Dani, Melanie Fertleman, Michael |
| author_facet | Pereira, Christopher Harris, Benjamin H L Di Giovannantonio, Matteo Rosadas, Carolina Short, Charlotte-Eve Quinlan, Rachael Sureda-Vives, Macià Fernandez, Natalia Day-Weber, Isaac Khan, Maryam Marchesin, Federica Katsanovskaja, Ksenia Parker, Eleanor Taylor, Graham P Tedder, Richard S McClure, Myra O Dani, Melanie Fertleman, Michael |
| author_sort | Pereira, Christopher |
| collection | PubMed |
| description | It is currently unknown how post-COVID-19 syndrome (PCS) may affect those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This longitudinal study includes healthcare staff who tested positive for SARS-CoV-2 between March and April 2020, with follow-up of their antibody titers and symptoms. More than half (21 of 38) had PCS after 7–8 months. There was no statistically significant difference between initial reverse-transcription polymerase chain reaction titers or serial antibody levels between those who did and those who did not develop PCS. This study highlights the relative commonality of PCS in healthcare workers and this should be considered in vaccination scheduling and workforce planning to allow adequate frontline staffing numbers. |
| format | Online Article Text |
| id | pubmed-7989400 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-79894002021-04-01 The Association Between Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Post–COVID-19 Syndrome in Healthcare Workers Pereira, Christopher Harris, Benjamin H L Di Giovannantonio, Matteo Rosadas, Carolina Short, Charlotte-Eve Quinlan, Rachael Sureda-Vives, Macià Fernandez, Natalia Day-Weber, Isaac Khan, Maryam Marchesin, Federica Katsanovskaja, Ksenia Parker, Eleanor Taylor, Graham P Tedder, Richard S McClure, Myra O Dani, Melanie Fertleman, Michael J Infect Dis Major Articles and Brief Reports It is currently unknown how post-COVID-19 syndrome (PCS) may affect those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This longitudinal study includes healthcare staff who tested positive for SARS-CoV-2 between March and April 2020, with follow-up of their antibody titers and symptoms. More than half (21 of 38) had PCS after 7–8 months. There was no statistically significant difference between initial reverse-transcription polymerase chain reaction titers or serial antibody levels between those who did and those who did not develop PCS. This study highlights the relative commonality of PCS in healthcare workers and this should be considered in vaccination scheduling and workforce planning to allow adequate frontline staffing numbers. Oxford University Press 2021-03-02 /pmc/articles/PMC7989400/ /pubmed/33675366 http://dx.doi.org/10.1093/infdis/jiab120 Text en © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| spellingShingle | Major Articles and Brief Reports Pereira, Christopher Harris, Benjamin H L Di Giovannantonio, Matteo Rosadas, Carolina Short, Charlotte-Eve Quinlan, Rachael Sureda-Vives, Macià Fernandez, Natalia Day-Weber, Isaac Khan, Maryam Marchesin, Federica Katsanovskaja, Ksenia Parker, Eleanor Taylor, Graham P Tedder, Richard S McClure, Myra O Dani, Melanie Fertleman, Michael The Association Between Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Post–COVID-19 Syndrome in Healthcare Workers |
| title | The Association Between Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Post–COVID-19 Syndrome in Healthcare Workers |
| title_full | The Association Between Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Post–COVID-19 Syndrome in Healthcare Workers |
| title_fullStr | The Association Between Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Post–COVID-19 Syndrome in Healthcare Workers |
| title_full_unstemmed | The Association Between Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Post–COVID-19 Syndrome in Healthcare Workers |
| title_short | The Association Between Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Post–COVID-19 Syndrome in Healthcare Workers |
| title_sort | association between antibody response to severe acute respiratory syndrome coronavirus 2 infection and post–covid-19 syndrome in healthcare workers |
| topic | Major Articles and Brief Reports |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989400/ https://www.ncbi.nlm.nih.gov/pubmed/33675366 http://dx.doi.org/10.1093/infdis/jiab120 |
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