Subtype-Specific Off-Label Treatment of Rosacea

We present 2 cases of rosacea that were successfully managed with off-label treatment. The first is a case of painful, exuding papulopustular lesions of the nose treated with rifaximin, and the other is a case of severe, debilitating and painful flushing treated with sumatriptan. The cases support p...

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Autores principales: Wienholtz, Nita, Ashina, Messoud, Thyssen, Jacob P., Egeberg, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989675/
https://www.ncbi.nlm.nih.gov/pubmed/33790755
http://dx.doi.org/10.1159/000511984
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author Wienholtz, Nita
Ashina, Messoud
Thyssen, Jacob P.
Egeberg, Alexander
author_facet Wienholtz, Nita
Ashina, Messoud
Thyssen, Jacob P.
Egeberg, Alexander
author_sort Wienholtz, Nita
collection PubMed
description We present 2 cases of rosacea that were successfully managed with off-label treatment. The first is a case of painful, exuding papulopustular lesions of the nose treated with rifaximin, and the other is a case of severe, debilitating and painful flushing treated with sumatriptan. The cases support previous notions that gastrointestinal comorbidities may be related to papulopustular lesions and that flushing may be related to neurogenic inflammation and migraine. The cases also imply that a new approach to rosacea management, based on endotypes and comorbidities, may be warranted.
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spelling pubmed-79896752021-03-30 Subtype-Specific Off-Label Treatment of Rosacea Wienholtz, Nita Ashina, Messoud Thyssen, Jacob P. Egeberg, Alexander Case Rep Dermatol Single Case We present 2 cases of rosacea that were successfully managed with off-label treatment. The first is a case of painful, exuding papulopustular lesions of the nose treated with rifaximin, and the other is a case of severe, debilitating and painful flushing treated with sumatriptan. The cases support previous notions that gastrointestinal comorbidities may be related to papulopustular lesions and that flushing may be related to neurogenic inflammation and migraine. The cases also imply that a new approach to rosacea management, based on endotypes and comorbidities, may be warranted. S. Karger AG 2021-02-16 /pmc/articles/PMC7989675/ /pubmed/33790755 http://dx.doi.org/10.1159/000511984 Text en Copyright © 2021 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Wienholtz, Nita
Ashina, Messoud
Thyssen, Jacob P.
Egeberg, Alexander
Subtype-Specific Off-Label Treatment of Rosacea
title Subtype-Specific Off-Label Treatment of Rosacea
title_full Subtype-Specific Off-Label Treatment of Rosacea
title_fullStr Subtype-Specific Off-Label Treatment of Rosacea
title_full_unstemmed Subtype-Specific Off-Label Treatment of Rosacea
title_short Subtype-Specific Off-Label Treatment of Rosacea
title_sort subtype-specific off-label treatment of rosacea
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989675/
https://www.ncbi.nlm.nih.gov/pubmed/33790755
http://dx.doi.org/10.1159/000511984
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