Activated factor X targeted stored in platelets as an effective gene therapy strategy for both hemophilia A and B

BACKGROUND: Treatment of hemophiliacs with inhibitors remains challenging, and new treatments are in urgent need. Coagulation factor X plays a critical role in the downstream of blood coagulation cascade, which could serve as a bypassing agent for hemophilia therapy. Base on platelet‐targeted gene t...

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Detalles Bibliográficos
Autores principales: Wang, Dawei, Shao, Xiaohu, Wang, Qiang, Pan, Xiaohong, Dai, Yujun, Yao, Shuxian, Yin, Tong, Wang, Zhugang, Zhu, Jiang, Xi, Xiaodong, Chen, Zhu, Chen, Saijuan, Zhang, Guowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989710/
https://www.ncbi.nlm.nih.gov/pubmed/33783994
http://dx.doi.org/10.1002/ctm2.375

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