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A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery
Trichoblastomas are rare dermal neoplasms usually found on the scalp and face. Histology shows a proliferation of small basaloid cells arranged in cords or fields surrounded by cellular stroma. Trichoblastomas are usually not aggressive, but trichoblastic carcinomas arising from preexisting trichobl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989768/ https://www.ncbi.nlm.nih.gov/pubmed/33790756 http://dx.doi.org/10.1159/000512871 |
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author | Leeman, Annemiek de Cuba, Erienne M.V. Jaspars, Lies H. Quint, Koen D. Genders, Roel E. |
author_facet | Leeman, Annemiek de Cuba, Erienne M.V. Jaspars, Lies H. Quint, Koen D. Genders, Roel E. |
author_sort | Leeman, Annemiek |
collection | PubMed |
description | Trichoblastomas are rare dermal neoplasms usually found on the scalp and face. Histology shows a proliferation of small basaloid cells arranged in cords or fields surrounded by cellular stroma. Trichoblastomas are usually not aggressive, but trichoblastic carcinomas arising from preexisting trichoblastomas have been described and have been linked to basal cell carcinoma. We found a tumor with features of trichoblastoma with presence of Merkel cells, but with a deeply infiltrative growth pattern into the fat and muscle tissue, without significant architectural or cellular atypia. Tumors with similar growth patterns were previously described as deeply invasive trichoblastic neoplasms. It appears to be a new entity that has been described before but has not been fully characterized: low-grade trichoblastic carcinoma. This malignancy seems to show only locally aggressive growth. Radical excision was accomplished with Mohs micrographic surgery. |
format | Online Article Text |
id | pubmed-7989768 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-79897682021-03-30 A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery Leeman, Annemiek de Cuba, Erienne M.V. Jaspars, Lies H. Quint, Koen D. Genders, Roel E. Case Rep Dermatol Case and Review Trichoblastomas are rare dermal neoplasms usually found on the scalp and face. Histology shows a proliferation of small basaloid cells arranged in cords or fields surrounded by cellular stroma. Trichoblastomas are usually not aggressive, but trichoblastic carcinomas arising from preexisting trichoblastomas have been described and have been linked to basal cell carcinoma. We found a tumor with features of trichoblastoma with presence of Merkel cells, but with a deeply infiltrative growth pattern into the fat and muscle tissue, without significant architectural or cellular atypia. Tumors with similar growth patterns were previously described as deeply invasive trichoblastic neoplasms. It appears to be a new entity that has been described before but has not been fully characterized: low-grade trichoblastic carcinoma. This malignancy seems to show only locally aggressive growth. Radical excision was accomplished with Mohs micrographic surgery. S. Karger AG 2021-02-18 /pmc/articles/PMC7989768/ /pubmed/33790756 http://dx.doi.org/10.1159/000512871 Text en Copyright © 2021 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Case and Review Leeman, Annemiek de Cuba, Erienne M.V. Jaspars, Lies H. Quint, Koen D. Genders, Roel E. A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery |
title | A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery |
title_full | A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery |
title_fullStr | A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery |
title_full_unstemmed | A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery |
title_short | A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery |
title_sort | low-grade trichoblastic carcinoma treated with mohs micrographic surgery |
topic | Case and Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989768/ https://www.ncbi.nlm.nih.gov/pubmed/33790756 http://dx.doi.org/10.1159/000512871 |
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