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A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery

Trichoblastomas are rare dermal neoplasms usually found on the scalp and face. Histology shows a proliferation of small basaloid cells arranged in cords or fields surrounded by cellular stroma. Trichoblastomas are usually not aggressive, but trichoblastic carcinomas arising from preexisting trichobl...

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Autores principales: Leeman, Annemiek, de Cuba, Erienne M.V., Jaspars, Lies H., Quint, Koen D., Genders, Roel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989768/
https://www.ncbi.nlm.nih.gov/pubmed/33790756
http://dx.doi.org/10.1159/000512871
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author Leeman, Annemiek
de Cuba, Erienne M.V.
Jaspars, Lies H.
Quint, Koen D.
Genders, Roel E.
author_facet Leeman, Annemiek
de Cuba, Erienne M.V.
Jaspars, Lies H.
Quint, Koen D.
Genders, Roel E.
author_sort Leeman, Annemiek
collection PubMed
description Trichoblastomas are rare dermal neoplasms usually found on the scalp and face. Histology shows a proliferation of small basaloid cells arranged in cords or fields surrounded by cellular stroma. Trichoblastomas are usually not aggressive, but trichoblastic carcinomas arising from preexisting trichoblastomas have been described and have been linked to basal cell carcinoma. We found a tumor with features of trichoblastoma with presence of Merkel cells, but with a deeply infiltrative growth pattern into the fat and muscle tissue, without significant architectural or cellular atypia. Tumors with similar growth patterns were previously described as deeply invasive trichoblastic neoplasms. It appears to be a new entity that has been described before but has not been fully characterized: low-grade trichoblastic carcinoma. This malignancy seems to show only locally aggressive growth. Radical excision was accomplished with Mohs micrographic surgery.
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spelling pubmed-79897682021-03-30 A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery Leeman, Annemiek de Cuba, Erienne M.V. Jaspars, Lies H. Quint, Koen D. Genders, Roel E. Case Rep Dermatol Case and Review Trichoblastomas are rare dermal neoplasms usually found on the scalp and face. Histology shows a proliferation of small basaloid cells arranged in cords or fields surrounded by cellular stroma. Trichoblastomas are usually not aggressive, but trichoblastic carcinomas arising from preexisting trichoblastomas have been described and have been linked to basal cell carcinoma. We found a tumor with features of trichoblastoma with presence of Merkel cells, but with a deeply infiltrative growth pattern into the fat and muscle tissue, without significant architectural or cellular atypia. Tumors with similar growth patterns were previously described as deeply invasive trichoblastic neoplasms. It appears to be a new entity that has been described before but has not been fully characterized: low-grade trichoblastic carcinoma. This malignancy seems to show only locally aggressive growth. Radical excision was accomplished with Mohs micrographic surgery. S. Karger AG 2021-02-18 /pmc/articles/PMC7989768/ /pubmed/33790756 http://dx.doi.org/10.1159/000512871 Text en Copyright © 2021 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case and Review
Leeman, Annemiek
de Cuba, Erienne M.V.
Jaspars, Lies H.
Quint, Koen D.
Genders, Roel E.
A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery
title A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery
title_full A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery
title_fullStr A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery
title_full_unstemmed A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery
title_short A Low-Grade Trichoblastic Carcinoma Treated with Mohs Micrographic Surgery
title_sort low-grade trichoblastic carcinoma treated with mohs micrographic surgery
topic Case and Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989768/
https://www.ncbi.nlm.nih.gov/pubmed/33790756
http://dx.doi.org/10.1159/000512871
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